STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_0516Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: tdn:Suden_0836 diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: Q30SB7 Diguanylate cyclase (GGDEF domain); TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (402 aa)    
Predicted Functional Partners:
Slip_2001
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006674; KEGG: cth:Cthe_0129 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: B4BA01 Diguanylate cyclase and metal dependent phosphohydrolase; PFAM: HD domain.
 
 
 0.970
Slip_1793
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR006674:IPR003607; KEGG: cac:CAC3410 HD-GYP domain-containing protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: B7A5P3 Metal dependent phosphohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG.
 
 
 0.918
Slip_1776
Metal dependent phosphohydrolase; COGs: COG1639 signal transduction protein; InterPro IPR013976:IPR003607:IPR006675; KEGG: swo:Swol_1403 putative signal transduction protein; PFAM: Metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region; SPTR: Q0AX44 Putative signal transduction protein; TIGRFAM: metal dependent phophohydrolase; PFAM: HDOD domain; TIGRFAM: uncharacterized domain HDIG.
 
      0.896
Slip_1643
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR006674:IPR003607; KEGG: swo:Swol_1502 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Q0AWU9 Metal dependent phosphohydrolase; PFAM: HD domain.
 
 
 0.891
Slip_0016
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006674; KEGG: mta:Moth_2495 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Q2RFL2 Metal dependent phosphohydrolase; PFAM: HD domain.
 
 0.862
Slip_2132
Diguanylate phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633:IPR018842; KEGG: chy:CHY_0074 EAL domain-containing protein; PFAM: EAL domain protein; EAL-like; SMART: EAL domain protein; SPTR: Q3AFY8 EAL domain protein; PFAM: EAL domain; EAL-domain associated signalling protein domain.
  
 0.853
Slip_1590
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR006674:IPR003607; KEGG: swo:Swol_0647 HD-GYP domain-containing protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Q0AZ80 HD-GYP domain containing protein; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG.
 
 0.820
Slip_2119
Ammonium transporter; COGs: COG0004 Ammonia permease; InterPro IPR001905:IPR018047:IPR002229; KEGG: afu:AF1746 ammonium transporter (amt-2); PFAM: ammonium transporter; SPTR: O28528 Ammonium transporter (Amt-2); TIGRFAM: ammonium transporter; PFAM: Ammonium Transporter Family; TIGRFAM: ammonium transporter.
 
      0.806
Slip_0724
Putative PAS/PAC sensor protein; COGs: COG2206 HD-GYP domain; InterProIPR000014:IPR003018:IPR003607:IPR013767:IPR 006674:IPR006675; KEGG: sat:SYN_01234 response regulator receiver domain-containing protein; PFAM: metal-dependent phosphohydrolase HD sub domain; GAF domain protein; PAS fold domain protein; SMART: metal-dependent phosphohydrolase HD region; GAF domain protein; PAS domain containing protein; SPTR: Q2YZR2 Putative uncharacterized protein; TIGRFAM: PAS sensor protein; metal dependent phophohydrolase; PFAM: HD domain; GAF domain; PAS fold; TIGRFAM: PAS domain S-box; uncharact [...]
 
 
 0.782
Slip_2166
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006674; KEGG: swo:Swol_2150 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Q0AV13 Metal dependent phosphohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG.
 
 
 0.773
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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