STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Experiments
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[Homology]
Score
Slip_0659NADH dehydrogenase (quinone); COGs: COG3261 Ni Fe-hydrogenase III large subunit; InterPro IPR018194:IPR001135; KEGG: ate:Athe_1086 NADH-ubiquinone oxidoreductase chain 49kDa; PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; PRIAM: NADH dehydrogenase (quinone); SPTR: B9MR83 NADH-ubiquinone oxidoreductase chain 49kDa; PFAM: Respiratory-chain NADH dehydrogenase, 49 Kd subunit; Nickel-dependent hydrogenase. (359 aa)    
Predicted Functional Partners:
Slip_0657
NADH dehydrogenase (quinone); COGs: COG3260 Ni Fe-hydrogenase III small subunit; InterPro IPR006137; KEGG: dma:DMR_02750 Ech hydrogenase subunit EchC; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: C6MRU1 NADH ubiquinone oxidoreductase 20 kDa subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, B subunit.
 
 0.999
Slip_0656
Respiratory-chain NADH dehydrogenase subunit 1; COGs: COG0650 Formate hydrogenlyase subunit 4; InterPro IPR001694; KEGG: dau:Daud_1099 respiratory-chain NADH dehydrogenase, subunit 1; PFAM: respiratory-chain NADH dehydrogenase subunit 1; SPTR: B1I3Q1 Respiratory-chain NADH dehydrogenase, subunit 1; PFAM: NADH dehydrogenase.
 
 
 0.996
Slip_0660
4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); InterPro IPR017900:IPR001450:IPR017896; KEGG: tte:TTE0128 formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q8RDB3 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (Chain I); PFAM: 4Fe-4S binding domain.
 
 
 0.985
Slip_0658
NADH dehydrogenase (ubiquinone) 30 kDa subunit; InterPro IPR005829:IPR001268; KEGG: adg:Adeg_0552 hypothetical protein; PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; SPTR: C9RBS3 Putative uncharacterized protein; manually curated; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit.
 
 
 0.973
nuoC
NADH (or F420H2) dehydrogenase, subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.
 
 0.953
Slip_0655
NADH/Ubiquinone/plastoquinone (complex I); COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterPro IPR003916:IPR001516:IPR001750; KEGG: det:DET0860 hydrogenase, EchA subunit, putative; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; SPTR: Q3Z863 Hydrogenase, EchA subunit, putative; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus.
 
   
 0.943
nuoI
4Fe-4S ferredoxin iron-sulfur binding domain protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
 
 
 0.917
nuoB
NADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
 0.910
Slip_0043
InterPro IPR017896:IPR017900:IPR001450; KEGG: nth:Nther_0025 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: B2A312 4Fe-4S ferredoxin iron-sulfur binding domain protein.
  
 
 0.751
Slip_0736
NIL domain protein; InterProIPR009051:IPR017900:IPR018449:IPR001450:IPR 017896; KEGG: swo:Swol_1440 ferridoxin; PFAM: NIL domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q0AX07 Ferridoxin; PFAM: 4Fe-4S binding domain; NIL domain.
  
 
 0.751
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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