STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_0814Protein of unknown function DUF152; COGs: COG1496 conserved hypothetical protein; InterPro IPR011324:IPR003730; KEGG: dae:Dtox_1076 protein of unknown function DUF152; PFAM: protein of unknown function DUF152; SPTR: C8W494 Putative uncharacterized protein; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: conserved hypothetical protein TIGR00726; Belongs to the multicopper oxidase YfiH/RL5 family. (273 aa)    
Predicted Functional Partners:
Slip_0818
Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
  
 0.864
Slip_0815
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR011006:IPR001867; KEGG: swo:Swol_0951 response regulator receiver protein; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Q0AYD8 Response regulator receiver protein; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
       0.786
sepF
Protein of unknown function DUF552; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
  
 0.677
Slip_0817
KEGG: mta:Moth_0857 hypothetical protein; SPTR: Q2RK65 Putative uncharacterized protein; TIGRFAM: putative membrane fusion protein.
       0.625
Slip_0821
InterPro IPR003425; KEGG: swo:Swol_0956 protein of unknown function YGGT; PFAM: protein of unknown function YGGT; SPTR: Q0AYD3 Putative uncharacterized protein; PFAM: YGGT family.
  
  
 0.603
Slip_0816
COGs: COG5002 Signal transduction histidine kinase; InterProIPR000014:IPR003661:IPR003594:IPR009082:IPR 004358:IPR013656:IPR005467; KEGG: swo:Swol_0952 sensory box histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Q0AYD7 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS do [...]
       0.601
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
       0.596
Slip_0823
DivIVA domain protein; InterPro IPR007793:IPR019933; KEGG: swo:Swol_0958 cell division initiation protein; PFAM: DivIVA family protein; SPTR: Q0AYD1 Cell division initiation protein; TIGRFAM: DivIVA domain; PFAM: DivIVA protein; TIGRFAM: DivIVA domain.
  
  
 0.536
Slip_0813
Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
       0.484
nrdR
ATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
       0.432
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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