STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_1030Drug resistance transporter, EmrB/QacA subfamily; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701:IPR001411:IPR004638:IPR016196; KEGG: pth:PTH_2781 transporter; PFAM: major facilitator superfamily MFS_1; SPTR: A5CYH9 Hypothetical transporter; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily. (515 aa)    
Predicted Functional Partners:
Slip_2341
Secretion protein HlyD family protein; COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR003997:IPR006143; KEGG: aca:ACP_3452 transporter, MFP family; PFAM: secretion protein HlyD family protein; SPTR: A1HMI0 Secretion protein HlyD family protein; PFAM: HlyD family secretion protein; TIGRFAM: ABC exporter membrane fusion protein, DevB family.
 
 0.807
Slip_1029
Putative signal transduction protein with CBS domains; COGs: COG2524 transcriptional regulator protein; InterPro IPR000644; KEGG: mta:Moth_1134 signal transduction protein; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; SPTR: Q2RJE1 Putative signal transduction protein with CBS domains; PFAM: CBS domain.
       0.693
Slip_1028
4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG1600 Uncharacterized Fe-S protein; InterPro IPR017900:IPR001450:IPR009051:IPR017896; KEGG: dsa:Desal_2047 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: C6BVD2 4Fe-4S ferredoxin iron-sulfur binding domain protein; TIGRFAM: iron-sulfur cluster binding protein, putative.
       0.564
Slip_2082
Major facilitator superfamily MFS_1; COGs: COG2814 Arabinose efflux permease; InterPro IPR016196:IPR005829:IPR011701; KEGG: sus:Acid_4563 major facilitator transporter; PFAM: major facilitator superfamily MFS_1; SPTR: A1HRB5 Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily.
  
     0.520
Slip_1031
Molybdopterin oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR017900:IPR006655:IPR000283:IPR001041:IPR 019574:IPR001450:IPR006963:IPR006656:IPR017896; KEGG: swo:Swol_0785 NADH dehydrogenase I chain G; PFAM: molybdopterin oxidoreductase; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molybdopterin oxidoreductase Fe4S4 region; SPTR: Q0AYU8 NADH dehydrogenase I chain G; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Molybdopterin oxidoreductase; NADH-ubiquinone oxidoredu [...]
       0.511
Slip_1032
Formate dehydrogenase, alpha subunit; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterPro IPR006656:IPR006657:IPR006478:IPR009010; KEGG: swo:Swol_0786 formate dehydrogenase alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; SPTR: Q0AYU7 Formate dehydrogenase alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; TIGRFAM: formate dehydrogenase, alpha subunit, archaeal-type; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
       0.419
Slip_0238
Secretion protein HlyD family protein; COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: drm:Dred_3060 secretion protein HlyD family protein; PFAM: secretion protein HlyD family protein; SPTR: A4J909 Secretion protein HlyD family protein; PFAM: HlyD family secretion protein.
 
 
 0.412
rnj
RNA-metabolising metallo-beta-lactamase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
       0.409
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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