STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_1052Metallophosphoesterase; COGs: COG1692 conserved hypothetical protein; InterPro IPR004843:IPR005235; KEGG: swo:Swol_1251 hypothetical protein; PFAM: metallophosphoesterase; SPTR: Q0AXJ4 Putative uncharacterized protein; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: conserved hypothetical protein TIGR00282. (303 aa)    
Predicted Functional Partners:
rny
Metal dependent phosphohydrolase; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
  
  
 0.835
Slip_1053
COGs: COG2359 conserved hypothetical protein; InterPro IPR007347; KEGG: swo:Swol_1250 stage V sporulation protein S; PFAM: Stage V sporulation protein S; SPTR: Q0AXJ5 Stage V sporulation protein S; PFAM: Stage V sporulation protein S (SpoVS).
  
    0.620
cinA
Competence/damage-inducible protein CinA; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453:IPR008136:IPR008135; KEGG: swo:Swol_1257 hypothetical protein; PFAM: CinA domain protein; molybdopterin binding domain; SPTR: Q0AXI8 CinA-like protein; TIGRFAM: competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain.
       0.570
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
       0.526
Slip_1054
COGs: COG2355 Zn-dependent dipeptidase microsomal dipeptidase homolog; InterPro IPR000180:IPR008257; KEGG: swo:Swol_1249 Zn-dependent dipeptidase, microsomal dipeptidase-like protein; PFAM: peptidase M19 renal dipeptidase; PRIAM: Membrane dipeptidase; SPTR: Q0AXJ6 Thermostable dipeptidase. Metallo peptidase. MEROPS family M19; PFAM: Membrane dipeptidase (Peptidase family M19).
       0.510
Slip_1055
PHP domain protein; COGs: COG0613 metal-dependent phosphoesterase (PHP family); InterPro IPR003141:IPR004013:IPR016195; KEGG: swo:Swol_1248 PHP family metal-dependent phosphoesterase; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: Q0AXJ7 Metal-dependent phosphoesterases (PHP family); PFAM: PHP domain.
       0.425
folD
Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
      0.420
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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