node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Slip_0002 | mutL | Slip_0002 | Slip_1076 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.938 |
Slip_0002 | mutS | Slip_0002 | Slip_1073 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.987 |
Slip_0002 | polA | Slip_0002 | Slip_1695 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.999 |
Slip_0002 | recA | Slip_0002 | Slip_1050 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.934 |
Slip_0002 | topA | Slip_0002 | Slip_0944 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.879 |
Slip_1074 | Slip_1075 | Slip_1074 | Slip_1075 | Hydantoinase/oxoprolinase; COGs: COG0145 N-methylhydantoinase A/acetone carboxylase beta subunit; InterPro IPR008040:IPR002821; KEGG: swo:Swol_0975 hydantoinase/oxoprolinase; PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; SPTR: Q0AYB4 Hydantoinase/oxoprolinase; PFAM: Hydantoinase/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region. | COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: mtp:Mthe_1405 histone deacetylase superfamily protein; PFAM: histone deacetylase superfamily; SPTR: A0B906 Histone deacetylase superfamily; PFAM: Histone deacetylase domain. | 0.958 |
Slip_1074 | Slip_1077 | Slip_1074 | Slip_1077 | Hydantoinase/oxoprolinase; COGs: COG0145 N-methylhydantoinase A/acetone carboxylase beta subunit; InterPro IPR008040:IPR002821; KEGG: swo:Swol_0975 hydantoinase/oxoprolinase; PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; SPTR: Q0AYB4 Hydantoinase/oxoprolinase; PFAM: Hydantoinase/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region. | Protein of unknown function DUF548; InterPro IPR007536; KEGG: swo:Swol_0978 hypothetical protein; PFAM: protein of unknown function DUF548; SPTR: Q0AYB1 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF548). | 0.614 |
Slip_1074 | miaA | Slip_1074 | Slip_1078 | Hydantoinase/oxoprolinase; COGs: COG0145 N-methylhydantoinase A/acetone carboxylase beta subunit; InterPro IPR008040:IPR002821; KEGG: swo:Swol_0975 hydantoinase/oxoprolinase; PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; SPTR: Q0AYB4 Hydantoinase/oxoprolinase; PFAM: Hydantoinase/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.548 |
Slip_1074 | mutL | Slip_1074 | Slip_1076 | Hydantoinase/oxoprolinase; COGs: COG0145 N-methylhydantoinase A/acetone carboxylase beta subunit; InterPro IPR008040:IPR002821; KEGG: swo:Swol_0975 hydantoinase/oxoprolinase; PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; SPTR: Q0AYB4 Hydantoinase/oxoprolinase; PFAM: Hydantoinase/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.840 |
Slip_1074 | mutS | Slip_1074 | Slip_1073 | Hydantoinase/oxoprolinase; COGs: COG0145 N-methylhydantoinase A/acetone carboxylase beta subunit; InterPro IPR008040:IPR002821; KEGG: swo:Swol_0975 hydantoinase/oxoprolinase; PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; SPTR: Q0AYB4 Hydantoinase/oxoprolinase; PFAM: Hydantoinase/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.819 |
Slip_1075 | Slip_1074 | Slip_1075 | Slip_1074 | COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: mtp:Mthe_1405 histone deacetylase superfamily protein; PFAM: histone deacetylase superfamily; SPTR: A0B906 Histone deacetylase superfamily; PFAM: Histone deacetylase domain. | Hydantoinase/oxoprolinase; COGs: COG0145 N-methylhydantoinase A/acetone carboxylase beta subunit; InterPro IPR008040:IPR002821; KEGG: swo:Swol_0975 hydantoinase/oxoprolinase; PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; SPTR: Q0AYB4 Hydantoinase/oxoprolinase; PFAM: Hydantoinase/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region. | 0.958 |
Slip_1075 | Slip_1077 | Slip_1075 | Slip_1077 | COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: mtp:Mthe_1405 histone deacetylase superfamily protein; PFAM: histone deacetylase superfamily; SPTR: A0B906 Histone deacetylase superfamily; PFAM: Histone deacetylase domain. | Protein of unknown function DUF548; InterPro IPR007536; KEGG: swo:Swol_0978 hypothetical protein; PFAM: protein of unknown function DUF548; SPTR: Q0AYB1 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF548). | 0.595 |
Slip_1075 | miaA | Slip_1075 | Slip_1078 | COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: mtp:Mthe_1405 histone deacetylase superfamily protein; PFAM: histone deacetylase superfamily; SPTR: A0B906 Histone deacetylase superfamily; PFAM: Histone deacetylase domain. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.518 |
Slip_1075 | mutL | Slip_1075 | Slip_1076 | COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: mtp:Mthe_1405 histone deacetylase superfamily protein; PFAM: histone deacetylase superfamily; SPTR: A0B906 Histone deacetylase superfamily; PFAM: Histone deacetylase domain. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.815 |
Slip_1075 | mutS | Slip_1075 | Slip_1073 | COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: mtp:Mthe_1405 histone deacetylase superfamily protein; PFAM: histone deacetylase superfamily; SPTR: A0B906 Histone deacetylase superfamily; PFAM: Histone deacetylase domain. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.891 |
Slip_1077 | Slip_1074 | Slip_1077 | Slip_1074 | Protein of unknown function DUF548; InterPro IPR007536; KEGG: swo:Swol_0978 hypothetical protein; PFAM: protein of unknown function DUF548; SPTR: Q0AYB1 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF548). | Hydantoinase/oxoprolinase; COGs: COG0145 N-methylhydantoinase A/acetone carboxylase beta subunit; InterPro IPR008040:IPR002821; KEGG: swo:Swol_0975 hydantoinase/oxoprolinase; PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; SPTR: Q0AYB4 Hydantoinase/oxoprolinase; PFAM: Hydantoinase/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region. | 0.614 |
Slip_1077 | Slip_1075 | Slip_1077 | Slip_1075 | Protein of unknown function DUF548; InterPro IPR007536; KEGG: swo:Swol_0978 hypothetical protein; PFAM: protein of unknown function DUF548; SPTR: Q0AYB1 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF548). | COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: mtp:Mthe_1405 histone deacetylase superfamily protein; PFAM: histone deacetylase superfamily; SPTR: A0B906 Histone deacetylase superfamily; PFAM: Histone deacetylase domain. | 0.595 |
Slip_1077 | miaA | Slip_1077 | Slip_1078 | Protein of unknown function DUF548; InterPro IPR007536; KEGG: swo:Swol_0978 hypothetical protein; PFAM: protein of unknown function DUF548; SPTR: Q0AYB1 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF548). | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.928 |
Slip_1077 | mutL | Slip_1077 | Slip_1076 | Protein of unknown function DUF548; InterPro IPR007536; KEGG: swo:Swol_0978 hypothetical protein; PFAM: protein of unknown function DUF548; SPTR: Q0AYB1 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF548). | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.563 |
Slip_1077 | mutS | Slip_1077 | Slip_1073 | Protein of unknown function DUF548; InterPro IPR007536; KEGG: swo:Swol_0978 hypothetical protein; PFAM: protein of unknown function DUF548; SPTR: Q0AYB1 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF548). | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.563 |