STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_1088Protein of unknown function DUF2088; COGs: COG3875 conserved hypothetical protein; InterPro IPR018657; KEGG: sth:STH1673 hypothetical protein; PFAM: Protein of unknown function DUF2088; SPTR: Q67NT5 Putative uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2088). (423 aa)    
Predicted Functional Partners:
Slip_1769
1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR000031; KEGG: dhd:Dhaf_2912 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SPTR: Q24WP3 Putative uncharacterized protein; PFAM: AIR carboxylase.
 
  
 0.901
Slip_0678
COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: swo:Swol_1760 Zn-dependent hydrolase including glyoxylases; SPTR: Q0AW46 Zn-dependent hydrolase including glyoxylases; PFAM: Metallo-beta-lactamase superfamily.
     
  0.900
Slip_0770
Beta-lactamase-like protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: swo:Swol_0808 beta-lactamase-like protein; SPTR: Q0AYS5 Beta-lactamase-like protein; PFAM: Metallo-beta-lactamase superfamily.
     
  0.900
Slip_1160
Beta-lactamase domain-containing protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: dol:Dole_0336 beta-lactamase domain-containing protein; SPTR: C0GF39 Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily.
     
  0.900
Slip_1661
NAD synthase; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR005232:IPR003694:IPR014729; KEGG: chy:CHY_1281 hypothetical protein; PFAM: NAD synthase; SPTR: Q3ACL9 Putative uncharacterized protein; PFAM: NAD synthase; TIGRFAM: conserved hypothetical protein TIGR00268.
 
  
 0.891
larC
Protein of unknown function DUF111; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
 
  
 0.766
Slip_1087
FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterProIPR006094:IPR004113:IPR016166:IPR016164:IPR 016167:IPR016168; KEGG: swo:Swol_1013 D-lactate dehydrogenase (cytochrome); PFAM: FAD linked oxidase domain protein; SPTR: Q0AY77 D-lactate dehydrogenase (Cytochrome); PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD.
 
   
 0.740
Slip_2154
L-lactate permease family protein, putative; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
     
 0.629
Slip_0375
Cobalt ABC transporter, inner membrane subunit CbiQ; COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR012809:IPR003339; KEGG: mpd:MCP_1084 putative cobalt ABC transporter permease protein; PFAM: cobalt transport protein; SPTR: C9R9R1 Cobalt ABC transporter, inner membrane subunit CbiQ; TIGRFAM: cobalt ABC transporter, inner membrane subunit CbiQ; PFAM: Cobalt transport protein; TIGRFAM: cobalt ABC transporter, permease protein CbiQ.
  
  
 0.596
Slip_1086
Protein of unknown function DUF224 cysteine-rich region domain protein; COGs: COG0247 Fe-S oxidoreductase; InterProIPR017900:IPR001450:IPR004017:IPR012257:IPR 009051:IPR012285:IPR017896; KEGG: swo:Swol_1012 glycolate oxidase iron-sulfur subunit, putative; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q0AY78 Glycolate oxidase iron-sulfur subunit, putative; PFAM: Cysteine-rich domain.
      0.510
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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