STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_1125Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1050 aa)    
Predicted Functional Partners:
Slip_1127
Site-specific DNA-methyltransferase (adenine-specific); COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356:IPR002296; KEGG: dol:Dole_2236 N-6 DNA methylase; PFAM: N-6 DNA methylase; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: A1HQI1 N-6 DNA methylase; PFAM: N-6 DNA Methylase; HsdM N-terminal domain.
 
 
 0.999
Slip_1126
Restriction modification system DNA specificity domain protein; COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: mba:Mbar_A2665 type I restriction-modification system specificity subunit; PFAM: restriction modification system DNA specificity domain; SPTR: Q468X1 Type I restriction-modification system specificity subunit; PFAM: Type I restriction modification DNA specificity domain.
 
  
 0.994
Slip_1270
SMC domain protein; COGs: COG3593 ATP-dependent endonuclease of the OLD family; InterPro IPR003395:IPR007087; KEGG: ele:Elen_0801 SMC domain protein; PFAM: SMC domain protein; SPTR: C8WNB5 SMC domain protein.
 
    0.817
Slip_0088
Protein of unknown function DUF2081; COGs: COG3472 conserved hypothetical protein; InterPro IPR004919:IPR018651; KEGG: sti:Sthe_1561 protein of unknown function DUF262; PFAM: Protein of unknown function DUF2081; protein of unknown function DUF262; SPTR: D1C429 Putative uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2081); Protein of unknown function DUF262.
 
   0.603
Slip_1124
Radical SAM domain protein; COGs: COG1533 DNA repair photolyase; InterPro IPR007197; KEGG: pth:PTH_2598 DNA repair photolyase; PFAM: Radical SAM domain protein; SPTR: A5CYZ6 DNA repair photolyase; PFAM: Radical SAM superfamily.
       0.518
Slip_1128
Resolvase domain protein; COGs: COG1961 Site-specific recombinase DNA invertase Pin homologs; InterPro IPR006119:IPR011109; KEGG: pth:PTH_0693 site-specific recombinases; PFAM: Resolvase domain; Recombinase; SPTR: C6Q3S3 Resolvase domain protein; PFAM: Recombinase; Resolvase, N terminal domain.
       0.474
Slip_1129
Peptidoglycan-binding lysin domain protein; InterPro IPR002482:IPR018392; KEGG: glo:Glov_0582 peptidoglycan-binding LysM; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: C6Q3R9 Putative uncharacterized protein; PFAM: LysM domain.
       0.459
Slip_2195
Permease; COGs: COG0701 permease; InterPro IPR005524; KEGG: nth:Nther_0966 permease; PFAM: permease; SPTR: B2A0I9 Permease; PFAM: Predicted permease.
  
    0.418
Slip_0071
Protein of unknown function DUF559; COGs: COG1112 Superfamily I DNA and RNA helicase and helicase subunits; InterPro IPR011335:IPR007569; KEGG: sat:SYN_02909 DNA helicase; PFAM: protein of unknown function DUF559; SPTR: B7R5W0 Putative uncharacterized protein; PFAM: UvrD/REP helicase; Protein of unknown function (DUF559).
       0.406
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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