STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_1139Diguanylate cyclase/phosphodiesterase with GAF sensor; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR003018:IPR000160:IPR001633; KEGG: ava:Ava_4425 diguanylate cyclase/phosphodiesterase with FHA and GAF sensor; PFAM: EAL domain protein; GGDEF domain containing protein; GAF domain protein; SMART: EAL domain protein; GGDEF domain containing protein; GAF domain protein; SPTR: Q3M4R3 Diguanylate cyclase/phosphodiesterase with FHA and GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate [...] (1024 aa)    
Predicted Functional Partners:
Slip_0498
Diguanylate cyclase and metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterProIPR000014:IPR000160:IPR013767:IPR003018:IPR 013656:IPR006674:IPR000700:IPR001610:IPR003607; KEGG: drm:Dred_1552 diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain containing protein; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein; GAF domain protein; metal-dependent phosphohydrolase HD region; SPTR: A4J4S7 Diguan [...]
 
0.960
Slip_0885
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789:IPR000160:IPR011006; KEGG: cyh:Cyan8802_1169 response regulator receiver modulated diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; PRIAM: Diguanylate kinase; SMART: GGDEF domain containing protein; response regulator receiver; SPTR: C7QN79 Response regulator receiver modulated diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: Response regulator receiver domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
  
0.920
Slip_1312
Diguanylate cyclase and metal dependent phosphohydrolase; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterProIPR000014:IPR000700:IPR000160:IPR013767:IPR 006674; KEGG: chy:CHY_2195 sensory box protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: GGDEF domain containing protein; PAS domain containing protein; SPTR: Q3AA26 Sensory box protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: HD domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; digua [...]
 
 
 
0.912
Slip_2119
Ammonium transporter; COGs: COG0004 Ammonia permease; InterPro IPR001905:IPR018047:IPR002229; KEGG: afu:AF1746 ammonium transporter (amt-2); PFAM: ammonium transporter; SPTR: O28528 Ammonium transporter (Amt-2); TIGRFAM: ammonium transporter; PFAM: Ammonium Transporter Family; TIGRFAM: ammonium transporter.
 
      0.863
Slip_1419
MCP methyltransferase, CheR-type; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: swo:Swol_0695 protein-glutamate O-methyltransferase; PFAM: MCP methyltransferase CheR-type; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase CheR-type; SPTR: Q0AZ35 MCP methyltransferase, CheR-type; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain.
      0.856
Slip_1307
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR011006:IPR001789:IPR000160; KEGG: adg:Adeg_1202 response regulator receiver protein; PFAM: response regulator receiver; GGDEF domain containing protein; SMART: response regulator receiver; SPTR: C9R7N4 Response regulator receiver protein; PFAM: Response regulator receiver domain.
  
 
 0.843
Slip_2132
Diguanylate phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633:IPR018842; KEGG: chy:CHY_0074 EAL domain-containing protein; PFAM: EAL domain protein; EAL-like; SMART: EAL domain protein; SPTR: Q3AFY8 EAL domain protein; PFAM: EAL domain; EAL-domain associated signalling protein domain.
 
  
0.813
Slip_1119
Putative PAS/PAC sensor protein; COGs: COG2202 FOG: PAS/PAC domain; InterProIPR000014:IPR001610:IPR013656:IPR013767:IPR 000700; KEGG: swo:Swol_1938 PAS/PAC domain-containing protein; PFAM: PAS fold domain protein; PAS fold-4 domain protein; SPTR: Q0AVL9 PAS/PAC domain-like protein; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box.
 
 
 0.805
Slip_1571
Ammonium transporter; COGs: COG0004 Ammonia permease; InterPro IPR001905:IPR018047; KEGG: dae:Dtox_1019 ammonium transporter; PFAM: ammonium transporter; SPTR: C8W3D8 Ammonium transporter; TIGRFAM: ammonium transporter; PFAM: Ammonium Transporter Family; TIGRFAM: ammonium transporter.
 
      0.759
Slip_0724
Putative PAS/PAC sensor protein; COGs: COG2206 HD-GYP domain; InterProIPR000014:IPR003018:IPR003607:IPR013767:IPR 006674:IPR006675; KEGG: sat:SYN_01234 response regulator receiver domain-containing protein; PFAM: metal-dependent phosphohydrolase HD sub domain; GAF domain protein; PAS fold domain protein; SMART: metal-dependent phosphohydrolase HD region; GAF domain protein; PAS domain containing protein; SPTR: Q2YZR2 Putative uncharacterized protein; TIGRFAM: PAS sensor protein; metal dependent phophohydrolase; PFAM: HD domain; GAF domain; PAS fold; TIGRFAM: PAS domain S-box; uncharact [...]
   
 0.706
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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