STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_1390Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR015424:IPR004839:IPR004838:IPR015421; KEGG: swo:Swol_1205 putative aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Q0AXP0 Aminotransferase; PFAM: Aminotransferase class I and II. (398 aa)    
Predicted Functional Partners:
Slip_1391
Transcriptional regulator, AsnC family; COGs: COG1522 Transcriptional regulators; InterProIPR011008:IPR000485:IPR019887:IPR019888:IPR 011991; KEGG: swo:Swol_1206 AsnC family transcriptional regulator; PFAM: Transcription regulator, AsnC-type-like; SMART: Transcription regulator, AsnC-type; SPTR: Q0AXN9 Transcriptional regulator, AsnC family; PFAM: AsnC family.
 
  
 0.959
Slip_0010
COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterProIPR006140:IPR016040:IPR006139:IPR002912:IPR 006236; KEGG: swo:Swol_0009 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; PRIAM: Phosphoglycerate dehydrogenase; SPTR: Q0B0Y6 D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific [...]
 
 
 0.599
Slip_1506
COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR007267:IPR001173:IPR013838; KEGG: swo:Swol_1908 cell wall biosynthesis glycosyltransferase-like protein; PFAM: glycosyl transferase family 2; GtrA family protein; SPTR: Q0AVP9 Glycosyltransferases involved in cell wall biogenesis-like protein; PFAM: GtrA-like protein; Glycosyl transferase family 2.
 
   
 0.526
Slip_1389
KEGG: swo:Swol_1204 hypothetical protein; SPTR: Q0AXP1 Putative uncharacterized protein.
       0.518
nadE-2
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.501
Slip_1426
uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR000878:IPR003754:IPR003043:IPR014777:IPR 014776:IPR006366; KEGG: swo:Swol_0687 hypothetical protein; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Q0AZ42 Uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase.
  
  
 0.468
Slip_1393
COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: chy:CHY_1233 methylenetetrahydrofolate reductase family protein; PFAM: methylenetetrahydrofolate reductase; SPTR: Q3ACR3 Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
  
 0.466
Slip_1852
COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR020831:IPR020832:IPR020828:IPR020829:IPR 016040:IPR020830:IPR006424; KEGG: mta:Moth_0262 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Q2RLU2 Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase [...]
  
 
 0.429
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
    0.421
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
 
  
 0.414
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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