STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_1517Protein of unknown function DUF21; COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644:IPR002550:IPR005170; KEGG: dhd:Dhaf_3277 protein of unknown function DUF21; PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; SMART: CBS domain containing protein; SPTR: Q24VP6 Putative uncharacterized protein; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain. (439 aa)    
Predicted Functional Partners:
Slip_1518
Hypothetical protein.
       0.668
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.625
ybeY
Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.571
Slip_1721
Phosphoesterase PA-phosphatase related protein; COGs: COG1238 membrane protein; InterPro IPR015414:IPR000326:IPR016118; KEGG: drm:Dred_2300 hypothetical protein; PFAM: phosphoesterase PA-phosphatase related; SNARE associated Golgi protein; SMART: phosphoesterase PA-phosphatase related; SPTR: A4J6V7 Putative uncharacterized protein; PFAM: PAP2 superfamily; SNARE associated Golgi protein.
     
 0.533
Slip_1506
COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR007267:IPR001173:IPR013838; KEGG: swo:Swol_1908 cell wall biosynthesis glycosyltransferase-like protein; PFAM: glycosyl transferase family 2; GtrA family protein; SPTR: Q0AVP9 Glycosyltransferases involved in cell wall biogenesis-like protein; PFAM: GtrA-like protein; Glycosyl transferase family 2.
 
 
 0.529
Slip_1324
KEGG: bbe:BBR47_12660 hypothetical protein; SPTR: C0Z7K0 Putative uncharacterized protein; PFAM: Copper amine oxidase N-terminal domain.
   
    0.474
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.433
nadE-2
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.433
Slip_0025
COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterProIPR019734:IPR013026:IPR011990:IPR001173:IPR 001440:IPR013105; KEGG: adg:Adeg_0252 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide repeat; SPTR: C9RAZ4 Glycosyl transferase family 2; PFAM: Glycosyl transferase family 2; Tetratricopeptide repeat.
  
 
 0.431
Slip_0536
CBS domain containing protein; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR001667:IPR003156:IPR000644:IPR002646; KEGG: swo:Swol_1420 polyA polymerase family protein; PFAM: CBS domain containing protein; phosphoesterase DHHA1; phosphoesterase RecJ domain protein; Polynucleotide adenylyltransferase region; SMART: CBS domain containing protein; SPTR: Q0AX27 PolyA polymerase family protein; PFAM: DHHA1 domain; DHH family; CBS domain; Poly A polymerase head domain; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
    0.423
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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