STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_1874Transketolase domain protein; COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR013838:IPR005474; KEGG: swo:Swol_0243 transketolase-like protein; PFAM: Transketolase domain protein; SPTR: Q0B0B0 Transketolase subunit A; PFAM: Transketolase, thiamine diphosphate binding domain. (277 aa)    
Predicted Functional Partners:
Slip_1873
Transketolase central region; COGs: COG3958 Transketolase C-terminal subunit; InterPro IPR009014:IPR015941:IPR005475:IPR005476; KEGG: swo:Swol_0244 transketolase-like protein; PFAM: Transketolase central region; Transketolase domain protein; SPTR: Q0B0A9 Transketolase subunit B; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
 0.999
Slip_0868
COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR011060:IPR000056:IPR013785; KEGG: swo:Swol_1223 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Q0AXM2 Ribulose-5-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase.
 
 0.996
Slip_2308
Fructose-1,6-bisphosphatase, class II; COGs: COG1494 Fructose-1 6-bisphosphatase/sedoheptulose 1 7-bisphosphatase and related protein; InterPro IPR004464; KEGG: swo:Swol_2409 fructose 1,6-bisphosphatase II; PFAM: GlpX family protein; PRIAM: Fructose-bisphosphatase; SPTR: Q0AUA6 Putative uncharacterized protein; TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: Bacterial fructose-1,6-bisphosphatase, glpX-encoded; TIGRFAM: fructose-1,6-bisphosphatase, class II.
 
   
  0.946
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
    
 0.933
Slip_2294
Sugar-phosphate isomerase, RpiB/LacA/LacB family; COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500:IPR004785; KEGG: chy:CHY_2558 ribose-5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: Q3A933 Ribose 5-phosphate isomerase B; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family.
    
 0.912
Slip_2310
Fructose-1,6-bisphosphate aldolase, class II; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771:IPR011289:IPR013785; KEGG: swo:Swol_2411 fructose-1,6-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Q0AUA4 Fructose-bisphosphate aldolase; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist.
    
 0.911
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
    
 0.910
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
    
 0.907
pfkA
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
    
 0.907
pfkA-2
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.907
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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