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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_1908Conserved hypothetical protein; InterPro IPR012657; KEGG: hna:Hneap_1490 hypothetical protein; SPTR: Q64E33 Putative uncharacterized protein; PFAM: S23 ribosomal protein; TIGRFAM: conserved hypothetical protein TIGR02436. (119 aa)    
Predicted Functional Partners:
Slip_1966
KEGG: rba:RB3569 hypothetical protein; SPTR: Q7UU16 Putative uncharacterized protein.
  
     0.670
Slip_1909
COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR013384:IPR001492; KEGG: chy:CHY_0972 flagellar hook-associated protein 3; PFAM: flagellin domain protein; SPTR: Q3ADG5 Flagellar hook-associated protein 3; TIGRFAM: flagellar hook-associated protein 3; manually curated; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region; TIGRFAM: flagellar hook-associated protein 3.
       0.662
Slip_1907
KEGG: swo:Swol_0194 hypothetical protein; SPTR: Q0B0F8 Putative uncharacterized protein.
       0.568
Slip_1910
COGs: COG1256 Flagellar hook-associated protein; InterPro IPR002371:IPR001444:IPR010930; KEGG: swo:Swol_0192 flagellar hook-associated protein-like protein; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; SPTR: Q0B0G0 Flagellar hook-associated protein-like protein; TIGRFAM: flagellar hook-associated protein FlgK; PFAM: Flagella basal body rod protein; Domain of unknown function (DUF1078); TIGRFAM: flagellar hook-associated protein FlgK; Belongs to the flagella basal body rod proteins family.
       0.429
csrA
Carbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
       0.415
fliW
Protein of unknown function DUF180; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
       0.407
Slip_0869
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
       0.406
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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