STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_1915COGs: COG4098 Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein); InterPro IPR014021:IPR001650; KEGG: mta:Moth_0224 DEAD/DEAH box helicase-like; SPTR: Q2RLY0 DEAD/DEAH box helicase-like. (619 aa)    
Predicted Functional Partners:
Slip_1914
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: swo:Swol_0188 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Q0B0G4 Phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein.
  
  
 0.913
Slip_1667
Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR019554:IPR010994:IPR003583:IPR004509; KEGG: swo:Swol_1596 competence protein ComEA helix-hairpin-helix region; PFAM: Soluble ligand binding domain; SPTR: Q0AWK6 Competence protein ComEA helix-hairpin-helix region; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: General secretion pathway protein K; SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein.
   
  
 0.750
Slip_1666
DNA internalization-related competence protein ComEC/Rec2; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477:IPR004797; KEGG: swo:Swol_1595 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: Q0AWK7 DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
   
  
 0.745
Slip_0401
COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR007831:IPR001482:IPR003593; KEGG: mta:Moth_1554 type II secretion system protein E; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SMART: AAA ATPase; SPTR: Q2RI76 Type II secretion system protein E; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain.
   
  
 0.726
Slip_1185
COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR007831:IPR001482; KEGG: tte:TTE1262 pili biogenesis protein PilB-like ATPase; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SPTR: Q8RAG1 Predicted ATPases involved in pili biogenesis, PilB homologs; PFAM: GSPII_E N-terminal domain; Type II/IV secretion system protein; TIGRFAM: general secretory pathway protein E.
   
  
 0.726
Slip_2347
COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR016027:IPR011344:IPR000424:IPR012340; KEGG: swo:Swol_2539 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Q0ATX7 Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb).
  
  
 0.689
Slip_0265
Hypothetical protein; InterPro IPR000983:IPR012902; KEGG: pjd:Pjdr2_2101 hypothetical protein; SPTR: C6Q646 Tfp pilus assembly protein PilE-like protein; PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain.
   
  
 0.649
Slip_1182
Hypothetical protein; InterPro IPR001120:IPR012902; KEGG: bav:BAV0340 general secretion pathway protein I; SPTR: B4X1B2 General secretion pathway protein I; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain.
   
  
 0.647
Slip_1186
Conserved hypothetical protein; InterPro IPR001120:IPR012902; KEGG: ckr:CKR_1012 hypothetical protein; SPTR: B9E0N8 Putative uncharacterized protein; PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain.
   
  
 0.647
Slip_0264
Type II secretion system F domain protein; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR001992:IPR003004:IPR018076; KEGG: mta:Moth_1552 type II secretion system protein; PFAM: Type II secretion system F domain; SPTR: Q2RI78 Type II secretion system protein; PFAM: Bacterial type II secretion system protein F domain.
   
  
 0.603
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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