STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Slip_1955Transcriptional regulator, TetR family; InterProIPR011075:IPR009057:IPR012287:IPR015893:IPR 001647; KEGG: swo:Swol_0177 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: Q0B0H5 Putative transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family; YsiA-like protein, C-terminal region. (191 aa)    
Predicted Functional Partners:
Slip_1957
Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143:IPR000089; KEGG: swo:Swol_0175 hypothetical protein; PFAM: secretion protein HlyD family protein; SPTR: Q0B0H7 Putative uncharacterized protein; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
   
 0.631
Slip_2342
Transcriptional regulator, TetR family; COGs: COG1309 Transcriptional regulator; InterPro IPR009057:IPR011075:IPR001647:IPR012287; KEGG: dal:Dalk_4836 transcriptional regulator, TetR family; PFAM: regulatory protein TetR; SPTR: C1SP64 Transcriptional regulator, COG1309; PFAM: Bacterial regulatory proteins, tetR family.
  
     0.622
Slip_1954
KEGG: adg:Adeg_1338 hypothetical protein; SPTR: C9R816 Putative uncharacterized protein.
       0.581
Slip_1956
Acriflavin resistance protein; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: swo:Swol_0176 acriflavin resistance protein; PFAM: acriflavin resistance protein; SPTR: Q0B0H6 Acriflavin resistance protein; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium); Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
     
 0.562
Slip_1953
Nucleotidyl transferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR011004:IPR005835:IPR001451; KEGG: swo:Swol_2137 mannose-1-phosphate guanyltransferase; PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; SPTR: Q0AV26 Mannose-1-phosphate guanyltransferase; PFAM: Nucleotidyl transferase.
       0.534
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
   
    0.439
Slip_0498
Diguanylate cyclase and metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterProIPR000014:IPR000160:IPR013767:IPR003018:IPR 013656:IPR006674:IPR000700:IPR001610:IPR003607; KEGG: drm:Dred_1552 diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain containing protein; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein; GAF domain protein; metal-dependent phosphohydrolase HD region; SPTR: A4J4S7 Diguan [...]
   
 
 0.411
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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