STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_2001Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006674; KEGG: cth:Cthe_0129 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: B4BA01 Diguanylate cyclase and metal dependent phosphohydrolase; PFAM: HD domain. (194 aa)    
Predicted Functional Partners:
Slip_0516
Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: tdn:Suden_0836 diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: Q30SB7 Diguanylate cyclase (GGDEF domain); TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
 0.970
Slip_0885
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789:IPR000160:IPR011006; KEGG: cyh:Cyan8802_1169 response regulator receiver modulated diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; PRIAM: Diguanylate kinase; SMART: GGDEF domain containing protein; response regulator receiver; SPTR: C7QN79 Response regulator receiver modulated diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: Response regulator receiver domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
   
 0.932
Slip_1251
Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: bbe:BBR47_52070 hypothetical protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: C0Z6I5 Putative uncharacterized protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
 0.791
Slip_1107
Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: aae:aq_429 hypothetical protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: O66743 Putative uncharacterized protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
 0.782
Slip_1139
Diguanylate cyclase/phosphodiesterase with GAF sensor; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR003018:IPR000160:IPR001633; KEGG: ava:Ava_4425 diguanylate cyclase/phosphodiesterase with FHA and GAF sensor; PFAM: EAL domain protein; GGDEF domain containing protein; GAF domain protein; SMART: EAL domain protein; GGDEF domain containing protein; GAF domain protein; SPTR: Q3M4R3 Diguanylate cyclase/phosphodiesterase with FHA and GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate [...]
 
   
 0.655
Slip_0498
Diguanylate cyclase and metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterProIPR000014:IPR000160:IPR013767:IPR003018:IPR 013656:IPR006674:IPR000700:IPR001610:IPR003607; KEGG: drm:Dred_1552 diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain containing protein; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein; GAF domain protein; metal-dependent phosphohydrolase HD region; SPTR: A4J4S7 Diguan [...]
 
 
0.497
Slip_2132
Diguanylate phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633:IPR018842; KEGG: chy:CHY_0074 EAL domain-containing protein; PFAM: EAL domain protein; EAL-like; SMART: EAL domain protein; SPTR: Q3AFY8 EAL domain protein; PFAM: EAL domain; EAL-domain associated signalling protein domain.
  
  
 0.428
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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