STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_2010COGs: COG2003 DNA repair protein; InterPro IPR001405; KEGG: drm:Dred_2549 DNA repair protein RadC; PFAM: DNA repair protein RadC; SPTR: A4J7K6 UPF0758 protein Dred_2549; PFAM: Protein of unknown function (DUF2466); TIGRFAM: DNA repair protein radc; Belongs to the UPF0758 family. (166 aa)    
Predicted Functional Partners:
Slip_0686
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
  
 0.685
Slip_0689
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
  
 0.681
Slip_1914
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: swo:Swol_0188 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Q0B0G4 Phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein.
 
    0.646
Slip_2009
Hypothetical protein; KEGG: cla:Cla_1442 NADH-quinone oxidoreductase, D subunit; SPTR: B9KDW9 NADH-quinone oxidoreductase, D subunit.
       0.642
Slip_2011
Domain of unknown function DUF1738; COGs: COG4227 Antirestriction protein; InterPro IPR017113:IPR013610; KEGG: dae:Dtox_2455 domain of unknown function DUF1738; PFAM: domain of unknown function DUF1738; SPTR: C3CUG2 Putative uncharacterized protein; PFAM: Domain of unknown function (DUF1738).
       0.541
cinA
Competence/damage-inducible protein CinA; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453:IPR008136:IPR008135; KEGG: swo:Swol_1257 hypothetical protein; PFAM: CinA domain protein; molybdopterin binding domain; SPTR: Q0AXI8 CinA-like protein; TIGRFAM: competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain.
     
 0.486
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
   
 0.455
Slip_0943
DNA protecting protein DprA; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: swo:Swol_0839 Rossmann-fold nucleotide-binding protein involved in DNA uptake; PFAM: SMF family protein; SPTR: Q0AYP6 Rossmann-fold nucleotide-binding protein involved in DNA uptake; TIGRFAM: DNA protecting protein DprA; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA.
   
  
 0.453
Slip_1666
DNA internalization-related competence protein ComEC/Rec2; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477:IPR004797; KEGG: swo:Swol_1595 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: Q0AWK7 DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
  
  
 0.446
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
   
 0.437
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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