STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_2011Domain of unknown function DUF1738; COGs: COG4227 Antirestriction protein; InterPro IPR017113:IPR013610; KEGG: dae:Dtox_2455 domain of unknown function DUF1738; PFAM: domain of unknown function DUF1738; SPTR: C3CUG2 Putative uncharacterized protein; PFAM: Domain of unknown function (DUF1738). (281 aa)    
Predicted Functional Partners:
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
 
      0.627
Slip_2024
TRAG family protein; COGs: COG3505 Type IV secretory pathway VirD4 protein; InterPro IPR007121:IPR003688; KEGG: pth:PTH_2488 type IV secretory pathway, VirD4 components; PFAM: TRAG family protein; SPTR: A5CZ99 Type IV secretory pathway, VirD4 components; PFAM: TraG/TraD family.
 
    0.568
Slip_2010
COGs: COG2003 DNA repair protein; InterPro IPR001405; KEGG: drm:Dred_2549 DNA repair protein RadC; PFAM: DNA repair protein RadC; SPTR: A4J7K6 UPF0758 protein Dred_2549; PFAM: Protein of unknown function (DUF2466); TIGRFAM: DNA repair protein radc; Belongs to the UPF0758 family.
       0.541
Slip_2012
Protein of unknown function DUF2442; InterPro IPR018841; KEGG: mta:Moth_0363 molybdopterin-guanine dinucleotide biosynthesis protein A-like; PFAM: Protein of unknown function DUF2442; SPTR: Q2RLJ2 Molybdopterin-guanine dinucleotide biosynthesis protein A-like; PFAM: Protein of unknown function (DUF2442).
       0.495
Slip_2013
KEGG: mta:Moth_0362 hypothetical protein; SPTR: Q2RLJ3 Putative uncharacterized protein.
       0.495
Slip_2009
Hypothetical protein; KEGG: cla:Cla_1442 NADH-quinone oxidoreductase, D subunit; SPTR: B9KDW9 NADH-quinone oxidoreductase, D subunit.
       0.439
Slip_0785
COGs: COG1907 sugar kinase; InterPro IPR020568; KEGG: pth:PTH_0622 sugar kinases; SPTR: A5D4L9 Predicted archaeal sugar kinases; TIGRFAM: beta-RFAP synthase.
  
     0.419
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.406
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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