STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (285 aa)    
Predicted Functional Partners:
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
 0.999
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 0.999
argD
COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterProIPR015424:IPR004636:IPR015422:IPR015421:IPR 005814; KEGG: swo:Swol_2288 acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Q0AUM5 Acetylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 0.996
Slip_2174
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
 
  
 0.985
argH
COGs: COG0165 Argininosuccinate lyase; InterProIPR008948:IPR003031:IPR000362:IPR009049:IPR 020557; KEGG: dae:Dtox_0572 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: C8W637 Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
 
  
 0.977
argG
COGs: COG0137 Argininosuccinate synthase; InterPro IPR001518:IPR014729:IPR018223; KEGG: chy:CHY_2260 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Q3A9W5 Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; manually curated; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
  
 0.977
Slip_2173
GCN5-related N-acetyltransferase; COGs: COG0456 Acetyltransferase; InterPro IPR016181:IPR000182; KEGG: swo:Swol_2174 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Q0AUY9 Acetyltransferase; PFAM: Acetyltransferase (GNAT) family.
  
 
 0.964
Slip_1325
COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR015424:IPR005814:IPR015421; KEGG: mta:Moth_1785 aminotransferase; PFAM: aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Q2RHK3 Aminotransferase; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.916
argR
Arginine repressor, ArgR; Regulates arginine biosynthesis genes.
  
  
 0.865
Slip_2067
Aminotransferase class-III; COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterProIPR015424:IPR016040:IPR015421:IPR005814:IPR 006151; KEGG: swo:Swol_0440 putative class-III aminotransferase; PFAM: aminotransferase class-III; Shikimate/quinate 5-dehydrogenase; SPTR: Q0AZS7 Aminotransferase; PFAM: Aminotransferase class-III.
  
 0.830
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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