STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_2277SpoIID/LytB domain protein; COGs: COG2385 Sporulation protein and related protein; InterPro IPR014225:IPR013486:IPR013693; KEGG: chy:CHY_2541 stage II sporulation protein D; PFAM: Stage II sporulation D domain protein; SPTR: Q3A950 Stage II sporulation protein D; TIGRFAM: SpoIID/LytB domain protein; stage II sporulation protein D; PFAM: Stage II sporulation protein; TIGRFAM: SpoIID/LytB domain; stage II sporulation protein D. (309 aa)    
Predicted Functional Partners:
Slip_2276
Sporulation transcriptional regulator SpoIIID; InterPro IPR014208:IPR018356; KEGG: swo:Swol_2375 stage III sporulation protein D; SPTR: Q0AUE0 Stage III sporulation protein D; TIGRFAM: sporulation transcriptional regulator SpoIIID; PFAM: Stage III sporulation protein D; TIGRFAM: sporulation transcriptional regulator SpoIIID.
 
   
 0.896
Slip_1470
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
  
 0.828
Slip_2200
COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508:IPR014234; KEGG: swo:Swol_2295 N-acetylmuramoyl-L-alanine amidase-like protein; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; SPTR: Q0AUL8 N-acetylmuramoyl-L-alanine amidase-like protein; TIGRFAM: N-acetylmuramoyl-L-alanine amidase CwlD; PFAM: N-acetylmuramoyl-L-alanine amidase; TIGRFAM: N-acetylmuramoyl-L-alanine amidase CwlD.
  
 0.754
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.729
Slip_0414
Stage III sporulation protein AA; COGs: COG3854 conserved hypothetical protein; InterPro IPR014217:IPR003593; KEGG: swo:Swol_0550 stage III sporulation protein spoIIIAA; SMART: AAA ATPase; SPTR: Q0AZH0 Stage III sporulation protein spoIIIAA; TIGRFAM: stage III sporulation protein AA; TIGRFAM: stage III sporulation protein AA.
  
  
 0.722
Slip_1657
Stage II sporulation protein P; InterPro IPR010897; KEGG: swo:Swol_1586 hypothetical protein; PFAM: Stage II sporulation P family protein; SPTR: Q0AWL6 Putative uncharacterized protein; TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation protein P (SpoIIP); TIGRFAM: stage II sporulation protein P.
  
  
 0.645
Slip_0100
Stage II sporulation protein R; InterPro IPR014202; KEGG: swo:Swol_0063 pro-sigma-E processing factor spoIIR; PFAM: Sporulation stage II protein R; SPTR: Q0B0T3 Pro-sigma-E processing factor spoIIR; TIGRFAM: stage II sporulation protein R; PFAM: Stage II sporulation protein R (spore_II_R); TIGRFAM: stage II sporulation protein R.
  
   
 0.635
Slip_2279
KEGG: aoe:Clos_2556 hypothetical protein; SPTR: A8MJV5 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1779).
       0.622
murA-2
UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
     
 0.613
Slip_0491
Stage II sporulation protein M; InterPro IPR014196:IPR018062:IPR002798; KEGG: swo:Swol_0605 uncharacterized membrane protein; PFAM: protein of unknown function DUF95 transmembrane; SPTR: Q0AZC0 Uncharacterized membrane protein; TIGRFAM: stage II sporulation protein M; PFAM: Integral membrane protein DUF95; TIGRFAM: stage II sporulation protein M.
      
 0.605
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.