STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_2295COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR017867:IPR000106; KEGG: adg:Adeg_0069 protein tyrosine phosphatase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: C9RAD6 Protein tyrosine phosphatase; PFAM: Low molecular weight phosphotyrosine protein phosphatase. (170 aa)    
Predicted Functional Partners:
Slip_2294
Sugar-phosphate isomerase, RpiB/LacA/LacB family; COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500:IPR004785; KEGG: chy:CHY_2558 ribose-5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: Q3A933 Ribose 5-phosphate isomerase B; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family.
 
    0.909
mcsB
ATP:guanido phosphotransferase; Catalyzes the specific phosphorylation of arginine residues in proteins.
 
  
 0.781
Slip_2270
UvrB/UvrC protein; COGs: COG3880 Uncharacterized protein with conserved CXXC pairs; InterPro IPR001943; KEGG: swo:Swol_2369 hypothetical protein; PFAM: UvrB/UvrC protein; SPTR: Q0AUE6 Putative uncharacterized protein; PFAM: UvrB/uvrC motif.
 
   
 0.778
Slip_2296
Protein of unknown function DUF204; Probably functions as a manganese efflux pump.
       0.756
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
    0.724
Slip_2297
Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
       0.719
prmC
protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
       0.719
Slip_2300
Protein of unknown function DUF1385; COGs: COG3872 metal-dependent protein; InterPro IPR010787; KEGG: swo:Swol_2398 hypothetical protein; PFAM: protein of unknown function DUF1385; SPTR: Q0AUB7 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1385).
       0.663
Slip_0846
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763:IPR016156:IPR004099:IPR013027; KEGG: afl:Aflv_0303 multidomain redox protein (NAD(FAD)-dependent oxidoreductase; rhodanese domain; SirA-like redox domain; peroxiredoxin domain); PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: B7GG08 Multidomain redox protein (NAD(FAD)-dependent oxidoreductase; Rhodanese domain; S [...]
   
 
 0.634
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.620
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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