STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slip_2314Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (400 aa)    
Predicted Functional Partners:
ddl
D-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
 
 0.958
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/ D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
   
 0.934
Slip_1784
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
  
 
0.920
Slip_2315
Methicillin resistance protein; COGs: COG2348 Uncharacterized protein involved in methicillin resistance; InterPro IPR016181:IPR003447; KEGG: swo:Swol_2417 methicillin resistance protein; PFAM: Methicillin resistance protein; SPTR: Q0AU98 Methicillin resistance protein; PFAM: FemAB family.
     
 0.803
Slip_2313
Signal peptide peptidase SppA, 36K type; COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR004635:IPR002142; KEGG: swo:Swol_2415 periplasmic serine proteases (ClpP class); PFAM: peptidase S49; SPTR: Q0AUA0 Signal peptide peptidase A. Serine peptidase. MEROPS family S49; TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: Peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type.
       0.780
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
  
 0.613
Slip_0558
Protein of unknown function UPF0079; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: swo:Swol_1869 hypothetical protein; PFAM: protein of unknown function UPF0079; SPTR: Q0AVT7 Putative uncharacterized protein; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: conserved hypothetical nucleotide-binding protein.
 
  
 0.598
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
       0.563
Slip_2312
KEGG: swo:Swol_2413 hypothetical protein; SPTR: Q0AUA2 Putative uncharacterized protein; PFAM: Yip1 domain.
       0.550
murD
UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
 
 
 0.533
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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