STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR20029.1FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: ddi:DDB_G0268008 hypothetical protein; PFAM: FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase. (376 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 
 0.929
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.915
ADR21569.1
Glycine C-acetyltransferase; COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR004839: IPR001917; KEGG: chu:CHU_1310 2-amino-3-ketobutyrate CoA ligase (glycine acetyltransferase); PFAM: aminotransferase class I and II; PRIAM: Glycine C-acetyltransferase; SPTR: 8-amino-7-oxononanoate synthase; PFAM: Aminotransferase class I and II.
  
 
 0.907
ADR23063.1
2-amino-3-ketobutyrate coenzyme A ligase; COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR004839: IPR001917; KEGG: csc:Csac_1225 glycine C-acetyltransferase; PFAM: aminotransferase class I and II; PRIAM: Glycine C-acetyltransferase; SPTR: 2-amino-3-ketobutyrate coenzyme A ligase; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase.
  
 
 0.907
kbl
2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
  
 
 0.907
ADR22785.1
COGs: COG2008 Threonine aldolase; InterPro IPR001597; KEGG: dfe:Dfer_4745 threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Threonine aldolase; SPTR: Threonine aldolase; PFAM: Beta-eliminating lyase.
    
 0.905
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.729
ADR20030.1
Transporter, NhaC family; COGs: COG1757 Na+/H+ antiporter; InterPro IPR018461: IPR004770; KEGG: cat:CA2559_12548 Na+/H+ antiporter; PFAM: Na+/H+ antiporter NhaC-like; SPTR: Na+/H+ antiporter; TIGRFAM: Na+/H+ antiporter NhaC; PFAM: Na+/H+ antiporter family; TIGRFAM: Na+/H+ antiporter NhaC; TC 2.A.35.
       0.614
ADR20031.1
3'-5' exonuclease; COGs: COG0349 Ribonuclease D; InterPro IPR002562; KEGG: dsa:Desal_0122 3'-5' exonuclease; PFAM: 3'-5' exonuclease; SMART: 3'-5' exonuclease; SPTR: Putative uncharacterized protein; PFAM: 3'-5' exonuclease.
       0.614
ADR20028.1
KEGG: aav:Aave_4086 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.543
Your Current Organism:
Marivirga tractuosa
NCBI taxonomy Id: 643867
Other names: Flexibacter tractuosus DSM 4126, Flexibacter tractuosus IFO 15989, M. tractuosa DSM 4126, Marivirga tractuosa DSM 4126, Marivirga tractuosa IFO 15989, Marivirga tractuosa str. DSM 4126, Marivirga tractuosa strain DSM 4126
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.