STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
ADR20088.1Sodium/hydrogen exchanger; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153: IPR003148: IPR022272; KEGG: zpr:ZPR_0004 sodium/hydrogen exchanger family protein; PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; SPTR: Sodium/hydrogen exchanger family protein; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family. (611 aa)    
Predicted Functional Partners:
ADR21750.1
H(+)-transporting two-sector ATPase; COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: gfo:GFO_2532 V-type sodium ATP synthase subunit J; PFAM: cation transporter; PRIAM: H(+)-transporting two-sector ATPase; SPTR: V-type sodium ATP synthase subunit J; PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family.
  
 
 0.792
ADR21751.1
H(+)-transporting two-sector ATPase; COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: gfo:GFO_2532 V-type sodium ATP synthase subunit J; PFAM: cation transporter; PRIAM: H(+)-transporting two-sector ATPase; SPTR: V-type sodium ATP synthase subunit J; PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family.
  
 
 0.792
ADR22144.1
Kef-type potassium/proton antiporter, CPA2 family; COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR003148: IPR006037: IPR006153; KEGG: gfo:GFO_1965 KefB-and KefC-like glutathione-regulated potassium-efflux system protein; PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; TrkA-C domain protein; SPTR: KefB-and KefC-like glutathione-regulated potassium-efflux system protein; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; TrkA-C domain; TIGRFAM: transporter, monovalent cation:proton antiporter-2 (CPA2) family; TC 2.A.37.1.
  
 
 0.621
ADR22140.1
Cl- channel voltage-gated family protein; COGs: COG0038 Chloride channel protein EriC; InterPro IPR000644: IPR001807: IPR005829; KEGG: pdi:BDI_1743 putative chloride channel protein; PFAM: Cl- channel voltage-gated family protein; CBS domain containing protein; SPTR: Putative transport related, membrane protein; PFAM: CBS domain; Voltage gated chloride channel.
 
  
 0.541
ADR20089.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR001440: IPR003594: IPR019734: IPR 005467: IPR013026; KEGG: chu:CHU_3468 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; Tetratricopeptide TPR_1 repeat-containing protein; SMART: ATP-binding region ATPase domain protein; Tetratricopeptide repeat; SPTR: Tetratricopeptide repeat domain protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
   
 
 0.507
ADR20087.1
Transcriptional repressor, CopY family; COGs: COG3682 transcriptional regulator protein; InterPro IPR005650; KEGG: dfe:Dfer_3380 transcriptional repressor, CopY family; PFAM: Penicillinase repressor; SPTR: Transcriptional repressor, CopY family; PFAM: Penicillinase repressor.
       0.490
ADR22532.1
COGs: COG1587 Uroporphyrinogen-III synthase; InterPro IPR003754; KEGG: chu:CHU_0169 uroporphyrinogen-III synthase; PFAM: Uroporphyrinogen III synthase HEM4; SPTR: Possible uroporphyrinogen-III synthase; manually curated; PFAM: Uroporphyrinogen-III synthase HemD.
  
  
 0.481
ADR22612.1
NADH/Ubiquinone/plastoquinone (complex I); COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterPro IPR001516: IPR001750: IPR003916; KEGG: pvi:Cvib_1257 putative monovalent cation/H+ antiporter subunit A; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; SPTR: NADH dehydrogenase (Quinone); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus.
     
 0.443
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.438
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.437
Your Current Organism:
Marivirga tractuosa
NCBI taxonomy Id: 643867
Other names: Flexibacter tractuosus DSM 4126, Flexibacter tractuosus IFO 15989, M. tractuosa DSM 4126, Marivirga tractuosa DSM 4126, Marivirga tractuosa IFO 15989, Marivirga tractuosa str. DSM 4126, Marivirga tractuosa strain DSM 4126
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