STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR20131.1COGs: COG0847 DNA polymerase III epsilon subunit and related 3'-5' exonuclease; InterPro IPR013520: IPR006055; KEGG: dfe:Dfer_3900 DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; SPTR: DNA polymerase III epsilon chain; PFAM: Exonuclease. (267 aa)    
Predicted Functional Partners:
ADR21415.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.964
ADR23107.1
COGs: COG2812 DNA polymerase III gamma/tau subunits; KEGG: dfe:Dfer_3272 DNA polymerase III gamma/tau subunit; SPTR: Putative DNA polymerase III, delta subunit.
  
 0.956
ADR23331.1
COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004805: IPR006055: IPR003141: IPR013520: IPR 004013: IPR011708: IPR004365; KEGG: rbi:RB2501_04255 DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; Exonuclease RNase T and DNA polymerase III; nucleic acid binding OB-fold tRNA/helicase-type; SMART: phosphoesterase PHP domain protein; Exonuclease; SPTR: Putative DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; Exonuclease; OB-fold nucleic acid bi [...]
   
 0.949
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.947
ADR20332.1
COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR005790: IPR010372; KEGG: chu:CHU_1537 hypothetical protein; PFAM: DNA polymerase III delta; SPTR: Putative uncharacterized protein; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit.
  
 
 0.946
ADR20019.1
COGs: COG0847 DNA polymerase III epsilon subunit and related 3'-5' exonuclease; InterPro IPR013520: IPR000305: IPR006055: IPR006054; KEGG: cpi:Cpin_5498 DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; Excinuclease ABC C subunit domain protein; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; Excinuclease ABC C subunit domain protein; SPTR: DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease; GIY-YIG catalytic domain; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family.
     
0.906
ADR20130.1
Cytoplasmic peptidoglycan synthetase domain protein; COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR000713: IPR013221: IPR004101; KEGG: chu:CHU_1348 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diaminopimelate ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; SPTR:UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl -meso-diaminopimelateligase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain.
       0.798
ADR20573.1
KEGG: chu:CHU_1553 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.644
ADR20129.1
Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
 
  
 0.628
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
  
 0.573
Your Current Organism:
Marivirga tractuosa
NCBI taxonomy Id: 643867
Other names: Flexibacter tractuosus DSM 4126, Flexibacter tractuosus IFO 15989, M. tractuosa DSM 4126, Marivirga tractuosa DSM 4126, Marivirga tractuosa IFO 15989, Marivirga tractuosa str. DSM 4126, Marivirga tractuosa strain DSM 4126
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