STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADR20137.1Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR001440: IPR003661: IPR003594: IPR 019734: IPR005467: IPR013026; KEGG: zpr:ZPR_0864 histidine kinase; PFAM: ATP-binding region ATPase domain protein; Tetratricopeptide TPR_1 repeat-containing protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; Tetratricopeptide repeat; histidine kinase A domain protein; SPTR: Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Tetratricopeptide repeat. (621 aa)    
Predicted Functional Partners:
ADR20832.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 008207: IPR001610: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: chu:CHU_2784 multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Multi-sensor hybrid histid [...]
 
 
0.849
ADR23345.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: chu:CHU_3042 two-component response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Response regulator DrrA; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 0.846
ADR21659.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867: IPR005829; KEGG: cpi:Cpin_0693 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: DNA-binding response regulator RprY; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 0.829
ADR20064.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR001638: IPR003661: IPR003594: IPR 000014: IPR000909: IPR005467: IPR000700; KEGG: dba:Dbac_2309 PAS/PAC sensor hybrid histidine kinase; PFAM: extracellular solute-binding protein family 3; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: extracellular solute-binding protein family 3; ATP-binding region ATPase domain protein; SPTR: PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Bacterial extracell [...]
 
 
 0.825
ADR20405.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: cpi:Cpin_2586 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: DNA-binding response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 
 0.809
ADR20833.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: chu:CHU_2785 sensor for ctr capsule biosynthesis, histidine kinase acting on RcsB; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Sensor for ctr capsule biosynthesis, probable histidine kinase acting on RcsB; PFAM: Response regulator receiver domain.
 
 
 0.804
ADR20136.1
KEGG: cat:CA2559_10828 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated.
       0.773
ADR23673.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003594: IPR005467: IPR001427: IPR004358; KEGG: fjo:Fjoh_1956 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
    0.765
ADR22604.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003594: IPR005467: IPR011622: IPR011623: IPR 004358; KEGG: chu:CHU_2797 sensor kinase of Zn/Pb responsive two-component regulatory system; PFAM: Diverse 7TM receptor transmembrane region; Diverse 7TM receptor extracellular region 2; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Periplasmic Sensor Hybrid Histidine Kinase; PFAM: 7TM diverse intracellular signalling; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; 7TMR-DISM extracellular 2; His Kinase A (phosphoaccept [...]
  
    0.724
ADR21658.1
Integral membrane sensor signal transduction histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR004358: IPR003661: IPR003594: IPR005467; KEGG: cpi:Cpin_0694 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Putative two component system sensor histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
   0.689
Your Current Organism:
Marivirga tractuosa
NCBI taxonomy Id: 643867
Other names: Flexibacter tractuosus DSM 4126, Flexibacter tractuosus IFO 15989, M. tractuosa DSM 4126, Marivirga tractuosa DSM 4126, Marivirga tractuosa IFO 15989, Marivirga tractuosa str. DSM 4126, Marivirga tractuosa strain DSM 4126
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