STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR20201.1uracil-DNA glycosylase; COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; KEGG: cat:CA2559_10968 uracil-DNA glycosylase; SPTR: ABC transporter, substrate binding protein, nitrate/sulfonate; PFAM: NMT1/THI5 like. (317 aa)    
Predicted Functional Partners:
nbaC
3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family.
 
    0.715
kmo
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
  
   
 0.650
ADR23085.1
NADPH-dependent FMN reductase; COGs: COG0431 flavoprotein; InterPro IPR005025; KEGG: chu:CHU_2733 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: Putative flavoprotein; PFAM: NADPH-dependent FMN reductase.
  
  
 0.563
ADR20202.1
Peptidoglycan glycosyltransferase; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264: IPR001460; KEGG: zpr:ZPR_2556 bifunctional transglycosylase/transpeptidase penicillin-binding protein; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Bifunctional transglycosylase/transpeptidase penicillin-binding protein; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase.
       0.556
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
     0.542
ADR20200.1
Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
       0.474
ADR21178.1
Tryptophan 2,3-dioxygenase apoenzyme; COGs: COG3483 Tryptophan 2 3-dioxygenase (vermilion); InterPro IPR004981; KEGG: phe:Phep_0260 tryptophan 2 3-dioxygenase (vermilion); PFAM: tryptophan 23-dioxygenase; SPTR: Tryptophan 2,3-dioxygenase; PFAM: Tryptophan 2,3-dioxygenase.
 
     0.413
ADR22467.1
KEGG: cat:CA2559_02905 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.401
Your Current Organism:
Marivirga tractuosa
NCBI taxonomy Id: 643867
Other names: Flexibacter tractuosus DSM 4126, Flexibacter tractuosus IFO 15989, M. tractuosa DSM 4126, Marivirga tractuosa DSM 4126, Marivirga tractuosa IFO 15989, Marivirga tractuosa str. DSM 4126, Marivirga tractuosa strain DSM 4126
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