STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR20376.1COGs: COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; InterPro IPR001126: IPR017963; KEGG: fba:FIC_01143 DNA polymerase IV; PFAM: UMUC domain protein DNA-repair protein; PRIAM: DNA-directed DNA polymerase; SPTR: DNA-directed DNA polymerase; PFAM: impB/mucB/samB family C-terminal; impB/mucB/samB family. (379 aa)    
Predicted Functional Partners:
ADR20375.1
COGs: COG0587 DNA polymerase III alpha subunit; InterPro IPR004805: IPR004013: IPR011708: IPR003141; KEGG: fjo:Fjoh_3769 DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; SPTR: DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; TIGRFAM: DNA-directed DNA polymerase III (polc).
  
 0.955
ADR21415.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.795
ADR21049.1
3'-5' exonuclease, PolB; InterPro IPR019288; KEGG: rbi:RB2501_05965 hypothetical protein; PFAM: 3'-5' exonuclease, PolB-like; SPTR: Putative uncharacterized protein; PFAM: Predicted 3'-5' exonuclease related to the exonuclease domain of PolB.
   
 0.789
ADR23484.1
UMUC domain protein DNA-repair protein; InterPro IPR017963: IPR001126; KEGG: fjo:Fjoh_3568 DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; SPTR: DNA-directed DNA polymerase; PFAM: impB/mucB/samB family.
  
     0.676
ADR23331.1
COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004805: IPR006055: IPR003141: IPR013520: IPR 004013: IPR011708: IPR004365; KEGG: rbi:RB2501_04255 DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; Exonuclease RNase T and DNA polymerase III; nucleic acid binding OB-fold tRNA/helicase-type; SMART: phosphoesterase PHP domain protein; Exonuclease; SPTR: Putative DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; Exonuclease; OB-fold nucleic acid bi [...]
 
  
 0.615
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.595
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.574
ADR23486.1
Helix-turn-helix domain protein; InterPro IPR001387; KEGG: chu:CHU_1881 transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Transcriptional repressor LexA, putative; PFAM: Helix-turn-helix.
  
     0.528
ADR20377.1
Protein of unknown function DUF227; InterPro IPR004119: IPR015897; KEGG: dre:797003 hypothetical LOC797003; PFAM: protein of unknown function DUF227; SMART: CHK kinase-like; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF227).
       0.524
ADR20378.1
Inositol monophosphatase; COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase family; InterPro IPR000760: IPR020583; KEGG: caa:Caka_0241 inositol monophosphatase; PFAM: inositol monophosphatase; SPTR: Inositol monophosphatase family; PFAM: Inositol monophosphatase family.
       0.521
Your Current Organism:
Marivirga tractuosa
NCBI taxonomy Id: 643867
Other names: Flexibacter tractuosus DSM 4126, Flexibacter tractuosus IFO 15989, M. tractuosa DSM 4126, Marivirga tractuosa DSM 4126, Marivirga tractuosa IFO 15989, Marivirga tractuosa str. DSM 4126, Marivirga tractuosa strain DSM 4126
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