STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR20773.1ATP dependent helicase, Lhr family; COGs: COG1201 Lhr-like helicase; InterProIPR014021: IPR001650: IPR014001: IPR017170: IPR 011545: IPR013701; KEGG: gfo:GFO_3528 DEAD box helicase family protein; PFAM: DEAD/H associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: DEAD box helicase family protein; PFAM: Helicase conserved C-terminal domain; DEAD/H associated; DEAD/DEAH box helicase. (809 aa)    
Predicted Functional Partners:
ADR20772.1
COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR016059: IPR012310: IPR012309; KEGG: cpi:Cpin_6857 ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA ligase I, ATP-dependent (dnl1).
 
    0.951
ADR20775.1
Metallophosphoesterase; COGs: COG1407 ICC-like phosphoesterase; InterPro IPR004843; KEGG: chu:CHU_3526 ICC-like phosphoesterase; PFAM: metallophosphoesterase; SPTR: Putative uncharacterized protein; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: putative phosphoesterase, SbcD/Mre11-related.
 
    0.932
ADR21126.1
Metallo-beta-lactamase; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; KEGG: zpr:ZPR_0470 metallo-beta-lactamase; SPTR: Metallo-beta-lactamase.
 
    0.803
ADR20019.1
COGs: COG0847 DNA polymerase III epsilon subunit and related 3'-5' exonuclease; InterPro IPR013520: IPR000305: IPR006055: IPR006054; KEGG: cpi:Cpin_5498 DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; Excinuclease ABC C subunit domain protein; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; Excinuclease ABC C subunit domain protein; SPTR: DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease; GIY-YIG catalytic domain; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family.
  
  
 0.655
ADR20774.1
Protein of unknown function DUF2147; InterPro IPR019223; KEGG: cts:Ctha_2007 hypothetical protein; PFAM: Protein of unknown function DUF2147; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2147).
       0.645
ADR20771.1
Histidine kinase HAMP region domain protein; InterPro IPR003660; KEGG: ava:Ava_4696 GAF sensor hybrid histidine kinase; PFAM: histidine kinase HAMP region domain protein; SMART: histidine kinase HAMP region domain protein; SPTR: GAF Sensor Hybrid Histidine Kinase, putative; PFAM: HAMP domain; TIGRFAM: PAS domain S-box.
       0.620
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
   
    0.514
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
  
 0.413
ADR20776.1
RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: chu:CHU_0953 RNA polymerase, sigma-E factor; heat shock and oxidative stress; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: DNA-directed RNA polymerase specialized sigma subunit, putative; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. E [...]
       0.411
ADR20777.1
KEGG: chu:CHU_0952 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.411
Your Current Organism:
Marivirga tractuosa
NCBI taxonomy Id: 643867
Other names: Flexibacter tractuosus DSM 4126, Flexibacter tractuosus IFO 15989, M. tractuosa DSM 4126, Marivirga tractuosa DSM 4126, Marivirga tractuosa IFO 15989, Marivirga tractuosa str. DSM 4126, Marivirga tractuosa strain DSM 4126
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