STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ligADNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (671 aa)    
Predicted Functional Partners:
ADR20772.1
COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR016059: IPR012310: IPR012309; KEGG: cpi:Cpin_6857 ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA ligase I, ATP-dependent (dnl1).
    
 0.920
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
    0.804
ADR20819.1
KEGG: aas:Aasi_1370 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.789
leuS
COGs: COG0495 Leucyl-tRNA synthetase; InterPro IPR001412: IPR002300: IPR013155: IPR002302; KEGG: phe:Phep_3538 leucyl-tRNA synthetase; PFAM: tRNA synthetase valyl/leucyl anticodon-binding; aminoacyl-tRNA synthetase class Ia; SPTR: Leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family.
 
 
 
 0.774
menB
1,4-Dihydroxy-2-naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
 
    
 0.710
ADR20839.1
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016: IPR014017: IPR000212; KEGG: sli:Slin_5601 UvrD/REP helicase; PFAM: UvrD/REP helicase; SPTR: ATP-dependent DNA helicase; PFAM: UvrD/REP helicase.
 
  
 0.665
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
   
 0.648
ADR21214.1
COGs: COG3943 Virulence protein; InterPro IPR011204; KEGG: clj:CLJU_c00540 hypothetical protein; SPTR: Putative uncharacterized protein.
      0.601
ADR20815.1
COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016; KEGG: chu:CHU_3510 superfamily I DNA/RNA helicase; SPTR: Superfamily I DNA and RNA helicase; PFAM: UvrD/REP helicase.
  
  
 0.600
rpsR
SSU ribosomal protein S18P; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
 
    0.582
Your Current Organism:
Marivirga tractuosa
NCBI taxonomy Id: 643867
Other names: Flexibacter tractuosus DSM 4126, Flexibacter tractuosus IFO 15989, M. tractuosa DSM 4126, Marivirga tractuosa DSM 4126, Marivirga tractuosa IFO 15989, Marivirga tractuosa str. DSM 4126, Marivirga tractuosa strain DSM 4126
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