STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icmFMethylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1129 aa)    
Predicted Functional Partners:
ADR23765.1
COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006158: IPR006099: IPR006098: IPR006159; KEGG: lic:LIC20209 methylmalonyl-CoA mutase; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein; PRIAM: Methylmalonyl-CoA mutase; SPTR: Methylmalonyl-CoA mutase large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase C-terminal domain.
 
 
0.998
ADR23766.1
COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006099; KEGG: aps:CFPG_558 cobalamin-dependent methylmalonyl-CoA mutase large subunit; PFAM: methylmalonyl-CoA mutase; PRIAM: Methylmalonyl-CoA mutase; SPTR: Putative uncharacterized protein; PFAM: Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain.
 
 
0.886
ADR23357.1
methylmalonyl-CoA mutase metallochaperone MeaB; COGs: COG1703 Putative periplasmic protein kinase ArgK and related GTPase of G3E family; InterPro IPR005129; KEGG: bth:BT_4049 arginine/ornithine transport system ATPase; PFAM: ArgK protein; SPTR: Arginine/ornithine transport system ATPase; TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; TIGRFAM: LAO/AO transport system ATPase.
 
  
0.822
ADR21259.1
Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: fjo:Fjoh_2323 periplasmic binding protein; PFAM: periplasmic binding protein; SPTR: Periplasmic binding protein; PFAM: Periplasmic binding protein.
 
  
 0.789
ADR22499.1
COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR003702; KEGG: gfo:GFO_1424 4-hydroxybutyrate coenzyme A transferase; PFAM: acetyl-CoA hydrolase/transferase; SPTR: 4-Hydroxybutyrate CoA-transferase; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain.
  
  
 0.780
ADR21565.1
methylmalonyl-CoA epimerase; InterPro IPR004360: IPR017515; KEGG: sli:Slin_5823 methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Lactoylglutathione lyase; TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase.
 
  
 0.738
ADR21674.1
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176: IPR006108: IPR001753; KEGG: chu:CHU_3591 4-enzyme protein: 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxybutyryl-CoA epimerase; delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase; enoyl-CoA hydratase; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; Enoyl-CoA hydratase/isomerase; SPTR: 4-enzyme protein: 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxybutyryl-CoA epimerase; delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase; enoyl-CoA hydratase; PFAM: Enoyl-CoA hydratase/isome [...]
 
  
 0.658
ADR23309.1
COGs: COG0281 Malic enzyme; InterPro IPR012301: IPR012302: IPR002505: IPR012188; KEGG: chu:CHU_0027 malic enzyme; PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; SPTR: NADP-dependent malate dehydrogenase; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase.
     
 0.564
ADR20828.1
GCN5-related N-acetyltransferase; InterPro IPR000182; KEGG: bay:RBAM_031150 YvbK; PFAM: GCN5-related N-acetyltransferase; SPTR: IAA acetyltransferase; PFAM: Acetyltransferase (GNAT) family.
       0.555
ADR23595.1
COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterProIPR011822: IPR003726: IPR000489: IPR004223: IPR 006158: IPR003759; KEGG: gfo:GFO_0333 5-methyltetrahydrofolate--homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; Vitamin B12 dependent methionine synthase activation region; SPTR: 5-methyltetrahydrofolate:homocysteine methyltransferase-cobalamin binding domain; TIGRFAM: methionine synthase; PFAM: Pterin binding enzyme; Vi [...]
     
 0.548
Your Current Organism:
Marivirga tractuosa
NCBI taxonomy Id: 643867
Other names: Flexibacter tractuosus DSM 4126, Flexibacter tractuosus IFO 15989, M. tractuosa DSM 4126, Marivirga tractuosa DSM 4126, Marivirga tractuosa IFO 15989, Marivirga tractuosa str. DSM 4126, Marivirga tractuosa strain DSM 4126
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.