STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADR21028.1L-serine dehydratase, iron-sulfur-dependent, beta subunit; COGs: COG1760 L-serine deaminase; InterPro IPR004643: IPR005131; KEGG: bmq:BMQ_4227 L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: serine dehydratase beta chain; PRIAM: L-serine ammonia-lyase; SPTR: L-serine dehydratase beta subunit; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit. (225 aa)    
Predicted Functional Partners:
ADR21918.1
COGs: COG1760 L-serine deaminase; InterPro IPR004642: IPR005130; KEGG: aoe:Clos_1741 L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: serine dehydratase alpha chain; PRIAM: L-serine ammonia-lyase; SPTR: Probable L-serine dehydratase alpha subunit; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: Serine dehydratase alpha chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit.
 
  
  0.997
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.938
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.918
ADR20805.1
Cystathionine beta-synthase; COGs: COG0031 Cysteine synthase; InterPro IPR001216: IPR000644: IPR001926; KEGG: sli:Slin_5829 cystathionine beta-synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; CBS domain containing protein; SMART: CBS domain containing protein; SPTR: Cysteine synthase; PFAM: CBS domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: cystathionine beta-synthase.
  
 
 0.913
ADR20061.1
COGs: COG1045 Serine acetyltransferase; InterPro IPR001451; KEGG: chu:CHU_0685 serine O-acetyltransferase; PRIAM: Serine O-acetyltransferase; SPTR: Putative serine acetyltransferase; TIGRFAM: serine O-acetyltransferase.
     
 0.909
trpA
Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
   
 
 0.902
trpB
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
  0.900
ADR21726.1
CDP-alcohol phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462; KEGG: phe:Phep_3071 CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR:CDP-diacylglycerol-serine-O-phosphatidyltransf erase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
  0.900
ADR22640.1
Hypothetical protein; KEGG: hbu:Hbut_1584 transcriptional regulator; SPTR: Putative ParB-like nuclease domain protein; PFAM: ParB-like nuclease domain.
     
  0.900
ADR22839.1
COGs: COG0527 Aspartokinase; InterProIPR001048: IPR002912: IPR005106: IPR001342: IPR 001341: IPR011147: IPR018042: IPR019811; KEGG: cpi:Cpin_5429 aspartate kinase; PFAM: homoserine dehydrogenase; aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; TIGRFAM: aspartate kinase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, mo [...]
  
 
 0.839
Your Current Organism:
Marivirga tractuosa
NCBI taxonomy Id: 643867
Other names: Flexibacter tractuosus DSM 4126, Flexibacter tractuosus IFO 15989, M. tractuosa DSM 4126, Marivirga tractuosa DSM 4126, Marivirga tractuosa IFO 15989, Marivirga tractuosa str. DSM 4126, Marivirga tractuosa strain DSM 4126
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