STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR21256.13-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (338 aa)    
Predicted Functional Partners:
ADR21034.1
Phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218: IPR006268; KEGG: rmr:Rmar_0597 phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: Phospho-2-dehydro-3-deoxyheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase.
 
 
 0.988
ADR21258.1
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
 0.987
aroQ
3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
 
 0.985
ADR21255.1
COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR002701: IPR006218: IPR020822; KEGG: rbi:RB2501_03045 putative phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase; PFAM: Chorismate mutase, type II; DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: Putative chorismate mutase; PFAM: Chorismate mutase type II; DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase.
 
  
 0.983
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
 0.976
ADR22650.1
COGs: COG0169 Shikimate 5-dehydrogenase; InterPro IPR013708: IPR006151; KEGG: chu:CHU_0006 shikimate dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding domain protein; Shikimate/quinate 5-dehydrogenase; SPTR: Shikimate dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding domain; TIGRFAM: shikimate 5-dehydrogenase.
  
 0.951
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
  
 0.947
ADR21248.1
Chorismate mutase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR002701: IPR006218: IPR020822; KEGG: sli:Slin_5731 DAHP synthetase I/KdsA; PFAM: Chorismate mutase, type II; DAHP synthetase I/KDSA; SPTR: DAHP synthetase I/KDSA; PFAM: Chorismate mutase type II; DAHP synthetase I family.
 
  
 0.925
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
 
  
 0.792
ADR20302.1
COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: fjo:Fjoh_0515 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase.
 
  
 0.697
Your Current Organism:
Marivirga tractuosa
NCBI taxonomy Id: 643867
Other names: Flexibacter tractuosus DSM 4126, Flexibacter tractuosus IFO 15989, M. tractuosa DSM 4126, Marivirga tractuosa DSM 4126, Marivirga tractuosa IFO 15989, Marivirga tractuosa str. DSM 4126, Marivirga tractuosa strain DSM 4126
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.