STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
ADR21345.1Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR013026: IPR001440: IPR003594: IPR 004358: IPR019734; KEGG: gfo:GFO_0018 adenylate/guanylate cyclase catalytic domain-containing protein; PFAM: ATP-binding region ATPase domain protein; Tetratricopeptide TPR_1 repeat-containing protein; SMART: ATP-binding region ATPase domain protein; Tetratricopeptide repeat; SPTR: Secreted protein containing adenylate/guanylate cyclase catalytic domain; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (644 aa)    
Predicted Functional Partners:
ADR20832.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 008207: IPR001610: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: chu:CHU_2784 multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Multi-sensor hybrid histid [...]
 
 
0.808
ADR23345.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: chu:CHU_3042 two-component response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Response regulator DrrA; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
   0.782
ADR21344.1
KEGG: bbo:BBOV_II006600 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.777
ADR20833.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: chu:CHU_2785 sensor for ctr capsule biosynthesis, histidine kinase acting on RcsB; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Sensor for ctr capsule biosynthesis, probable histidine kinase acting on RcsB; PFAM: Response regulator receiver domain.
 
 
   0.764
ADR20064.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR001638: IPR003661: IPR003594: IPR 000014: IPR000909: IPR005467: IPR000700; KEGG: dba:Dbac_2309 PAS/PAC sensor hybrid histidine kinase; PFAM: extracellular solute-binding protein family 3; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: extracellular solute-binding protein family 3; ATP-binding region ATPase domain protein; SPTR: PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Bacterial extracell [...]
 
 
 
 0.758
ADR21659.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867: IPR005829; KEGG: cpi:Cpin_0693 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: DNA-binding response regulator RprY; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
   0.741
ADR20405.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: cpi:Cpin_2586 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: DNA-binding response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
  
   0.730
ADR23158.1
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: nfa:nfa1540 putative two-component system response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Putative two-component system response regulator; PFAM: Response regulator receiver domain.
  
   0.573
ADR20048.1
Signal transduction histidine kinase with CheB and CheR activity; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterProIPR000780: IPR000673: IPR013767: IPR003661: IPR 003594: IPR000014: IPR001610: IPR005467: IPR000700: IPR002052; KEGG: cts:Ctha_1653 signal transduction histidine kinase with CheB and CheR activity; PFAM: ATP-binding region ATPase domain protein; CheB methylesterase; MCP methyltransferase CheR-type; PAS fold domain protein; histidine kinase A domain protein; SMART: MCP methyltransferase CheR-type; PAS domain containing protein; PAC repeat-containing pr [...]
  
 
 0.564
ADR20344.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: dfe:Dfer_4011 two component transcriptional regulator, winged helix family; PFAM: transcriptional regulator domain-containing protein; response regulator receiver; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
  
   0.522
Your Current Organism:
Marivirga tractuosa
NCBI taxonomy Id: 643867
Other names: Flexibacter tractuosus DSM 4126, Flexibacter tractuosus IFO 15989, M. tractuosa DSM 4126, Marivirga tractuosa DSM 4126, Marivirga tractuosa IFO 15989, Marivirga tractuosa str. DSM 4126, Marivirga tractuosa strain DSM 4126
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