STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR22144.1Kef-type potassium/proton antiporter, CPA2 family; COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR003148: IPR006037: IPR006153; KEGG: gfo:GFO_1965 KefB-and KefC-like glutathione-regulated potassium-efflux system protein; PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; TrkA-C domain protein; SPTR: KefB-and KefC-like glutathione-regulated potassium-efflux system protein; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; TrkA-C domain; TIGRFAM: transporter, monovalent cation:proton antiporter-2 (CPA2) family; TC 2.A.37.1. (676 aa)    
Predicted Functional Partners:
ADR23049.1
NAD(P)H dehydrogenase (quinone); COGs: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: fjo:Fjoh_4532 NAD(P)H dehydrogenase (quinone); PFAM: NAD(P)H dehydrogenase (quinone); SPTR: NAD(P)H dehydrogenase (Quinone); PFAM: Flavodoxin-like fold.
  
 
 0.819
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
       0.661
ADR22141.1
Peptidase S41; COGs: COG0793 Periplasmic protease; InterPro IPR005151: IPR019825; KEGG: pdi:BDI_3195 hypothetical protein; PFAM: peptidase S41; SMART: peptidase S41; SPTR: Putative uncharacterized protein; PFAM: Peptidase family S41.
       0.642
ADR22142.1
Hypothetical protein; KEGG: tca:661133 similar to Metabotropic glutamate receptor precursor; SPTR: Putative uncharacterized protein.
       0.642
nhaA
Sodium/proton antiporter, NhaA family; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
 
   
 0.637
ADR20088.1
Sodium/hydrogen exchanger; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153: IPR003148: IPR022272; KEGG: zpr:ZPR_0004 sodium/hydrogen exchanger family protein; PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; SPTR: Sodium/hydrogen exchanger family protein; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family.
  
 
 0.621
ADR22839.1
COGs: COG0527 Aspartokinase; InterProIPR001048: IPR002912: IPR005106: IPR001342: IPR 001341: IPR011147: IPR018042: IPR019811; KEGG: cpi:Cpin_5429 aspartate kinase; PFAM: homoserine dehydrogenase; aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; TIGRFAM: aspartate kinase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, mo [...]
 
   
 0.582
ADR22140.1
Cl- channel voltage-gated family protein; COGs: COG0038 Chloride channel protein EriC; InterPro IPR000644: IPR001807: IPR005829; KEGG: pdi:BDI_1743 putative chloride channel protein; PFAM: Cl- channel voltage-gated family protein; CBS domain containing protein; SPTR: Putative transport related, membrane protein; PFAM: CBS domain; Voltage gated chloride channel.
     
 0.576
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.568
ADR20135.1
Citrate transporter; COGs: COG0471 Di- and tricarboxylate transporter; InterPro IPR004680: IPR006037: IPR001898; KEGG: zpr:ZPR_0525 TrkA domain protein; PFAM: Citrate transporter; TrkA-C domain protein; SPTR: TrkA domain protein; PFAM: Citrate transporter; TrkA-C domain.
  
  
 0.567
Your Current Organism:
Marivirga tractuosa
NCBI taxonomy Id: 643867
Other names: Flexibacter tractuosus DSM 4126, Flexibacter tractuosus IFO 15989, M. tractuosa DSM 4126, Marivirga tractuosa DSM 4126, Marivirga tractuosa IFO 15989, Marivirga tractuosa str. DSM 4126, Marivirga tractuosa strain DSM 4126
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