STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR22360.1COGs: COG0708 Exonuclease III; InterProIPR000097: IPR004808: IPR005135: IPR020847: IPR 020848; KEGG: coc:Coch_1451 exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: Exodeoxyribonuclease III; SPTR: Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). (255 aa)    
Predicted Functional Partners:
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 0.965
ADR21415.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.774
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.772
ADR22361.1
KEGG: sli:Slin_5517 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.738
ADR22362.1
Alkylhydroperoxidase like protein, AhpD family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
       0.734
ADR22569.1
A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
    
 0.721
ADR23191.1
InterPro IPR014127; KEGG: dfe:Dfer_5052 hypothetical protein; PFAM: Conserved hypothetical protein CHP02757; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2400); TIGRFAM: conserved hypothetical protein TIGR02757.
  
 0.672
ADR20772.1
COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR016059: IPR012310: IPR012309; KEGG: cpi:Cpin_6857 ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA ligase I, ATP-dependent (dnl1).
  
 
 0.670
ung
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
   
 0.667
ADR20557.1
Ribosomal large subunit pseudouridine synthase F; COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR000748: IPR002942: IPR006145: IPR018496; KEGG: zpr:ZPR_3830 ribosomal large subunit pseudouridine synthase F; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family.
  
    0.655
Your Current Organism:
Marivirga tractuosa
NCBI taxonomy Id: 643867
Other names: Flexibacter tractuosus DSM 4126, Flexibacter tractuosus IFO 15989, M. tractuosa DSM 4126, Marivirga tractuosa DSM 4126, Marivirga tractuosa IFO 15989, Marivirga tractuosa str. DSM 4126, Marivirga tractuosa strain DSM 4126
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