STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR22478.1COGs: COG1560 Lauroyl/myristoyl acyltransferase; InterPro IPR004960; KEGG: cpi:Cpin_2595 lipid A biosynthesis acyltransferase; PFAM: lipid A biosynthesis acyltransferase; SPTR: Lipid A biosynthesis acyltransferase; PFAM: Bacterial lipid A biosynthesis acyltransferase. (303 aa)    
Predicted Functional Partners:
ADR23114.1
Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
  
 0.979
ADR23502.1
acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.797
ADR22479.1
ABC transporter related protein; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR003593: IPR003439: IPR017940: IPR001140: IPR 017871; KEGG: sli:Slin_5540 ABC transporter related protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: HlyB/MsbA family ABC transporter; PFAM: ABC transporter; ABC transporter transmembrane region; TIGRFAM: ABC transporter, permease/ATP-binding protein.
  
  
 0.793
ADR23444.1
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.791
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
  
 0.784
lpxD
UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
   
 0.781
fabZ
3-hydroxyacyl-(acyl-carrier-protein) dehydratase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
 
   
 0.747
ADR20737.1
KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR000644: IPR001347: IPR004800; KEGG: tcx:Tcr_0503 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SPTR: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily.
 
   
 0.676
ADR20738.1
2-dehydro-3-deoxyphosphooctonate aldolase; COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; InterPro IPR006218: IPR006269; KEGG: pru:PRU_0445 3-deoxy-8-phosphooctulonate synthase; PFAM: DAHP synthetase I/KDSA; SPTR: Putative uncharacterized protein; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase.
 
  
 0.561
ADR22477.1
Conserved hypothetical protein CHP00730; COGs: COG1611 Rossmann fold nucleotide-binding protein; InterPro IPR005269; KEGG: sli:Slin_1915 hypothetical protein; PFAM: Conserved hypothetical protein CHP00730; SPTR: Putative uncharacterized protein; PFAM: Possible lysine decarboxylase; TIGRFAM: conserved hypothetical protein, DprA/Smf-related, family 1; conserved hypothetical protein, DprA/Smf-related, family 2; Belongs to the LOG family.
       0.561
Your Current Organism:
Marivirga tractuosa
NCBI taxonomy Id: 643867
Other names: Flexibacter tractuosus DSM 4126, Flexibacter tractuosus IFO 15989, M. tractuosa DSM 4126, Marivirga tractuosa DSM 4126, Marivirga tractuosa IFO 15989, Marivirga tractuosa str. DSM 4126, Marivirga tractuosa strain DSM 4126
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.