STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (342 aa)    
Predicted Functional Partners:
ADR23353.1
Uncharacterized protein family UPF0093; COGs: COG1981 membrane protein; InterPro IPR005265; KEGG: zpr:ZPR_0118 membrane protein, UPF0093; PFAM: Uncharacterised protein family UPF0093; SPTR: Uncharacterized protein family (UPF0093); PFAM: Uncharacterised protein family (UPF0093); TIGRFAM: conserved hypothetical integral membrane protein.
 
  
 0.936
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
   
 
 0.921
ADR23280.1
COGs: COG1239 Mg-chelatase subunit ChlI; KEGG: sli:Slin_0326 Mg-chelatase subunit ChlI-like protein; SPTR: Magnesium chelatase, subunit ChlI family protein; PFAM: Sigma-54 interaction domain.
  
 
 0.916
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.894
ADR21480.1
COGs: COG0408 Coproporphyrinogen III oxidase; InterPro IPR001260: IPR018375; KEGG: sli:Slin_2294 coproporphyrinogen oxidase; PFAM: coproporphyrinogen III oxidase; PRIAM: Coproporphyrinogen oxidase; SPTR: Coproporphyrinogen oxidase; PFAM: Coproporphyrinogen III oxidase.
 
   
 0.760
ADR20520.1
Amine oxidase; COGs: COG1233 Phytoene dehydrogenase and related protein; InterPro IPR002937; KEGG: mxa:MXAN_6060 amine oxidase, flavin-containing; PFAM: amine oxidase; SPTR: Oxidoreductase, FAD-binding protein; PFAM: Flavin containing amine oxidoreductase.
  
  
 0.741
ADR22574.1
Tetratricopeptide TPR_1 repeat-containing protein; InterPro IPR019734: IPR013026: IPR001440; KEGG: fba:FIC_01328 signal transduction histidine kinase; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: Two-component sensor histidine kinase.
   
 
 0.620
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.541
ADR22576.1
PAS sensor protein; InterPro IPR003018: IPR000014: IPR003660; KEGG: dae:Dtox_3786 GAF sensor hybrid histidine kinase; PFAM: GAF domain protein; histidine kinase HAMP region domain protein; SMART: GAF domain protein; SPTR: Chemotaxis protein; TIGRFAM: PAS sensor protein; PFAM: GAF domain.
       0.510
ADR21595.1
Porphobilinogen synthase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: sli:Slin_5386 porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; PRIAM: Porphobilinogen synthase; SPTR: Delta-aminolevulinic acid dehydratase; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
  
 0.434
Your Current Organism:
Marivirga tractuosa
NCBI taxonomy Id: 643867
Other names: Flexibacter tractuosus DSM 4126, Flexibacter tractuosus IFO 15989, M. tractuosa DSM 4126, Marivirga tractuosa DSM 4126, Marivirga tractuosa IFO 15989, Marivirga tractuosa str. DSM 4126, Marivirga tractuosa strain DSM 4126
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