node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADR20671.1 | ADR22708.1 | Ftrac_0669 | Ftrac_2730 | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: sli:Slin_1005 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: cat:CA2559_02840 6-pyruvoyl tetrahydrobiopterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | 0.948 |
ADR20671.1 | ADR23105.1 | Ftrac_0669 | Ftrac_3130 | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: sli:Slin_1005 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | COGs: COG3540 Phosphodiesterase/alkaline phosphatase D; KEGG: gfo:GFO_0789 phosphodiesterase/alkaline phosphatase D-like protein; SPTR: Alkaline phosphatase D domain protein; PFAM: PhoD-like phosphatase. | 0.900 |
ADR20671.1 | ADR23534.1 | Ftrac_0669 | Ftrac_3564 | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: sli:Slin_1005 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: chu:CHU_1390 6-pyruvoyltetrahydropterin synthase (6-pyruvoyl tetrahydrobiopterin) synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | 0.910 |
ADR20671.1 | folE | Ftrac_0669 | Ftrac_0670 | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: sli:Slin_1005 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | COGs: COG0302 GTP cyclohydrolase I; InterPro IPR018234: IPR020602: IPR001474; KEGG: dfe:Dfer_0468 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I. | 0.988 |
ADR20671.1 | hisI | Ftrac_0669 | Ftrac_3210 | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: sli:Slin_1005 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | phosphoribosyl-ATP diphosphatase; COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; InterPro IPR002496: IPR021130: IPR008179; KEGG: cpi:Cpin_1832 phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; SPTR: Phosphoribosyl-ATP diphosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family. | 0.408 |
ADR20671.1 | queE | Ftrac_0669 | Ftrac_2877 | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: sli:Slin_1005 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.974 |
ADR22707.1 | ADR22708.1 | Ftrac_2729 | Ftrac_2730 | Transcriptional regulator, BadM/Rrf2 family; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: rbi:RB2501_10797 rrf2 family protein (putative transcriptional regulator); PFAM: protein of unknown function UPF0074; SPTR: Rrf2 family protein (Putative transcriptional regulator); TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: Transcriptional regulator; TIGRFAM: rrf2 family protein (putative transcriptional regulator). | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: cat:CA2559_02840 6-pyruvoyl tetrahydrobiopterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | 0.654 |
ADR22708.1 | ADR20671.1 | Ftrac_2730 | Ftrac_0669 | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: cat:CA2559_02840 6-pyruvoyl tetrahydrobiopterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: sli:Slin_1005 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | 0.948 |
ADR22708.1 | ADR22707.1 | Ftrac_2730 | Ftrac_2729 | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: cat:CA2559_02840 6-pyruvoyl tetrahydrobiopterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | Transcriptional regulator, BadM/Rrf2 family; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: rbi:RB2501_10797 rrf2 family protein (putative transcriptional regulator); PFAM: protein of unknown function UPF0074; SPTR: Rrf2 family protein (Putative transcriptional regulator); TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: Transcriptional regulator; TIGRFAM: rrf2 family protein (putative transcriptional regulator). | 0.654 |
ADR22708.1 | ADR22879.1 | Ftrac_2730 | Ftrac_2903 | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: cat:CA2559_02840 6-pyruvoyl tetrahydrobiopterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR005834: IPR006402: IPR006439: IPR005833; KEGG: sli:Slin_0811 HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 3; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; [...] | 0.598 |
ADR22708.1 | ADR23105.1 | Ftrac_2730 | Ftrac_3130 | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: cat:CA2559_02840 6-pyruvoyl tetrahydrobiopterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | COGs: COG3540 Phosphodiesterase/alkaline phosphatase D; KEGG: gfo:GFO_0789 phosphodiesterase/alkaline phosphatase D-like protein; SPTR: Alkaline phosphatase D domain protein; PFAM: PhoD-like phosphatase. | 0.900 |
ADR22708.1 | ADR23534.1 | Ftrac_2730 | Ftrac_3564 | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: cat:CA2559_02840 6-pyruvoyl tetrahydrobiopterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: chu:CHU_1390 6-pyruvoyltetrahydropterin synthase (6-pyruvoyl tetrahydrobiopterin) synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | 0.910 |
ADR22708.1 | folE | Ftrac_2730 | Ftrac_0670 | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: cat:CA2559_02840 6-pyruvoyl tetrahydrobiopterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | COGs: COG0302 GTP cyclohydrolase I; InterPro IPR018234: IPR020602: IPR001474; KEGG: dfe:Dfer_0468 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I. | 0.946 |
ADR22708.1 | hisI | Ftrac_2730 | Ftrac_3210 | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: cat:CA2559_02840 6-pyruvoyl tetrahydrobiopterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | phosphoribosyl-ATP diphosphatase; COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; InterPro IPR002496: IPR021130: IPR008179; KEGG: cpi:Cpin_1832 phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; SPTR: Phosphoribosyl-ATP diphosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family. | 0.408 |
ADR22708.1 | queE | Ftrac_2730 | Ftrac_2877 | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: cat:CA2559_02840 6-pyruvoyl tetrahydrobiopterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.981 |
ADR22879.1 | ADR22708.1 | Ftrac_2903 | Ftrac_2730 | HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR005834: IPR006402: IPR006439: IPR005833; KEGG: sli:Slin_0811 HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 3; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; [...] | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: cat:CA2559_02840 6-pyruvoyl tetrahydrobiopterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | 0.598 |
ADR23105.1 | ADR20671.1 | Ftrac_3130 | Ftrac_0669 | COGs: COG3540 Phosphodiesterase/alkaline phosphatase D; KEGG: gfo:GFO_0789 phosphodiesterase/alkaline phosphatase D-like protein; SPTR: Alkaline phosphatase D domain protein; PFAM: PhoD-like phosphatase. | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: sli:Slin_1005 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | 0.900 |
ADR23105.1 | ADR22708.1 | Ftrac_3130 | Ftrac_2730 | COGs: COG3540 Phosphodiesterase/alkaline phosphatase D; KEGG: gfo:GFO_0789 phosphodiesterase/alkaline phosphatase D-like protein; SPTR: Alkaline phosphatase D domain protein; PFAM: PhoD-like phosphatase. | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: cat:CA2559_02840 6-pyruvoyl tetrahydrobiopterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | 0.900 |
ADR23105.1 | ADR23534.1 | Ftrac_3130 | Ftrac_3564 | COGs: COG3540 Phosphodiesterase/alkaline phosphatase D; KEGG: gfo:GFO_0789 phosphodiesterase/alkaline phosphatase D-like protein; SPTR: Alkaline phosphatase D domain protein; PFAM: PhoD-like phosphatase. | COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: chu:CHU_1390 6-pyruvoyltetrahydropterin synthase (6-pyruvoyl tetrahydrobiopterin) synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: 6-pyruvoyl tetrahydropterin synthase/QueD family protein. | 0.900 |
ADR23105.1 | folE | Ftrac_3130 | Ftrac_0670 | COGs: COG3540 Phosphodiesterase/alkaline phosphatase D; KEGG: gfo:GFO_0789 phosphodiesterase/alkaline phosphatase D-like protein; SPTR: Alkaline phosphatase D domain protein; PFAM: PhoD-like phosphatase. | COGs: COG0302 GTP cyclohydrolase I; InterPro IPR018234: IPR020602: IPR001474; KEGG: dfe:Dfer_0468 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I. | 0.923 |