STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (418 aa)    
Predicted Functional Partners:
ADR23595.1
COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterProIPR011822: IPR003726: IPR000489: IPR004223: IPR 006158: IPR003759; KEGG: gfo:GFO_0333 5-methyltetrahydrofolate--homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; Vitamin B12 dependent methionine synthase activation region; SPTR: 5-methyltetrahydrofolate:homocysteine methyltransferase-cobalamin binding domain; TIGRFAM: methionine synthase; PFAM: Pterin binding enzyme; Vi [...]
  
 
 0.946
ADR21748.1
DNA-cytosine methyltransferase; COGs: COG0270 Site-specific DNA methylase; InterPro IPR001525: IPR000551: IPR018117; KEGG: wch:wcw_1690 C-5 cytosine-specific DNA methylase; PFAM: C-5 cytosine-specific DNA methylase; regulatory protein MerR; PRIAM: DNA (cytosine-5-)-methyltransferase; SPTR: Cytosine-specific methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: MerR family regulatory protein; C-5 cytosine-specific DNA methylase; TIGRFAM: DNA-methyltransferase (dcm); DNA binding domain, excisionase family.
    
 0.924
ADR20111.1
Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: rmr:Rmar_1177 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Cys/Met metabolism PLP-dependent enzyme; PFAM: Cys/Met metabolism PLP-dependent enzyme.
   
 0.921
ADR20386.1
DNA-cytosine methyltransferase; COGs: COG0270 Site-specific DNA methylase; InterPro IPR001525: IPR018117; KEGG: cat:CA2559_00245 site-specific DNA-methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; SPTR: Cytosine-specific methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; TIGRFAM: DNA-methyltransferase (dcm); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
 0.909
ADR20432.1
DNA-cytosine methyltransferase; COGs: COG0270 Site-specific DNA methylase; InterPro IPR001525: IPR018117; KEGG: fps:FP2274 type II modification methyltransferase HpaII; PFAM: C-5 cytosine-specific DNA methylase; SPTR: Cytosine-specific methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; TIGRFAM: DNA-methyltransferase (dcm).
    
 0.909
ADR22125.1
DNA-cytosine methyltransferase; COGs: COG0270 Site-specific DNA methylase; InterPro IPR001525: IPR018117; KEGG: pdi:BDI_3001 site-specific DNA methylase; PFAM: C-5 cytosine-specific DNA methylase; SPTR: Cytosine-specific methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; TIGRFAM: DNA-methyltransferase (dcm).
    
 0.909
ADR23648.1
DNA-cytosine methyltransferase; COGs: COG0270 Site-specific DNA methylase; InterPro IPR001525: IPR018117; KEGG: smb:smi_0942 site-specific DNA methylase; PFAM: C-5 cytosine-specific DNA methylase; SPTR: Cytosine-specific methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; TIGRFAM: DNA-methyltransferase (dcm).
    
 0.909
ADR23650.1
DNA-cytosine methyltransferase; COGs: COG0270 Site-specific DNA methylase; InterPro IPR001525: IPR018117; KEGG: smb:smi_0944 site-specific DNA methylase; PFAM: C-5 cytosine-specific DNA methylase; SPTR: Cytosine-specific methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; TIGRFAM: DNA-methyltransferase (dcm).
    
 0.909
GafA
GafA; COGs: COG1956 GAF domain-containing protein; KEGG: phe:Phep_2040 GafA; GAF domain-containing protein; SPTR: GAF domain-containing protein involved in signal transduction.
     
  0.900
ispF
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
    
 0.800
Your Current Organism:
Marivirga tractuosa
NCBI taxonomy Id: 643867
Other names: Flexibacter tractuosus DSM 4126, Flexibacter tractuosus IFO 15989, M. tractuosa DSM 4126, Marivirga tractuosa DSM 4126, Marivirga tractuosa IFO 15989, Marivirga tractuosa str. DSM 4126, Marivirga tractuosa strain DSM 4126
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