STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR22841.1COGs: COG0498 Threonine synthase; InterPro IPR001926: IPR004450; KEGG: fjo:Fjoh_2573 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; PRIAM: Threonine synthase; SPTR: Threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase. (425 aa)    
Predicted Functional Partners:
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
 0.999
ADR22839.1
COGs: COG0527 Aspartokinase; InterProIPR001048: IPR002912: IPR005106: IPR001342: IPR 001341: IPR011147: IPR018042: IPR019811; KEGG: cpi:Cpin_5429 aspartate kinase; PFAM: homoserine dehydrogenase; aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; TIGRFAM: aspartate kinase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, mo [...]
 
 
 0.998
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.950
ADR21077.1
Aminotransferase class V; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
   
 0.933
ADR23689.1
COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; KEGG: dfe:Dfer_5113 aminotransferase class V; SPTR: Phosphoserine aminotransferase, Mycobacterial type, putative; PFAM: Aminotransferase class-V; TIGRFAM: phosphoserine aminotransferase, putative.
   
 0.933
ADR22785.1
COGs: COG2008 Threonine aldolase; InterPro IPR001597; KEGG: dfe:Dfer_4745 threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Threonine aldolase; SPTR: Threonine aldolase; PFAM: Beta-eliminating lyase.
  
 0.924
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
  
 0.796
ADR21136.1
COGs: COG0460 Homoserine dehydrogenase; InterPro IPR019811: IPR005106: IPR001342; KEGG: phe:Phep_1873 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; PRIAM: Homoserine dehydrogenase; SPTR: Homoserine dehydrogenase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain.
 
 
 0.778
ADR22375.1
Pyridoxal-5'-phosphate-dependent protein beta subunit; COGs: COG1171 Threonine dehydratase; InterPro IPR001926; KEGG: dfe:Dfer_2376 pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Putative threonine dehydratase; PFAM: Pyridoxal-phosphate dependent enzyme.
  
 
 0.752
ADR22485.1
COGs: COG0527 Aspartokinase; InterPro IPR001341: IPR001048: IPR018042; KEGG: cpi:Cpin_6874 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: Aspartokinase; TIGRFAM: aspartate kinase; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family.
 
 
 0.698
Your Current Organism:
Marivirga tractuosa
NCBI taxonomy Id: 643867
Other names: Flexibacter tractuosus DSM 4126, Flexibacter tractuosus IFO 15989, M. tractuosa DSM 4126, Marivirga tractuosa DSM 4126, Marivirga tractuosa IFO 15989, Marivirga tractuosa str. DSM 4126, Marivirga tractuosa strain DSM 4126
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