node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADR20099.1 | kdsB | Ftrac_0085 | Ftrac_3214 | COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR000106: IPR017867; KEGG: lil:LB035 low molecular weight phosphotyrosine protein phosphatase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: Phosphotyrosine protein phosphatase; PFAM: Low molecular weight phosphotyrosine protein phosphatase. | 3-deoxy-D-manno- octulosonatecytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.844 |
ADR20737.1 | ADR20738.1 | Ftrac_0735 | Ftrac_0736 | KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR000644: IPR001347: IPR004800; KEGG: tcx:Tcr_0503 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SPTR: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | 2-dehydro-3-deoxyphosphooctonate aldolase; COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; InterPro IPR006218: IPR006269; KEGG: pru:PRU_0445 3-deoxy-8-phosphooctulonate synthase; PFAM: DAHP synthetase I/KDSA; SPTR: Putative uncharacterized protein; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase. | 0.996 |
ADR20737.1 | ADR21114.1 | Ftrac_0735 | Ftrac_1119 | KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR000644: IPR001347: IPR004800; KEGG: tcx:Tcr_0503 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SPTR: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR005834: IPR010023: IPR006549; KEGG: mac:MA3766 acylneuraminate cytidylyltransferase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Phosphatase kdsC; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; HAD-superfamily hydrolase, subfamily IIIA. | 0.944 |
ADR20737.1 | ADR23114.1 | Ftrac_0735 | Ftrac_3139 | KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR000644: IPR001347: IPR004800; KEGG: tcx:Tcr_0503 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SPTR: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.852 |
ADR20737.1 | ADR23444.1 | Ftrac_0735 | Ftrac_3472 | KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR000644: IPR001347: IPR004800; KEGG: tcx:Tcr_0503 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SPTR: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.846 |
ADR20737.1 | ADR23502.1 | Ftrac_0735 | Ftrac_3532 | KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR000644: IPR001347: IPR004800; KEGG: tcx:Tcr_0503 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SPTR: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.828 |
ADR20737.1 | kdsB | Ftrac_0735 | Ftrac_3214 | KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR000644: IPR001347: IPR004800; KEGG: tcx:Tcr_0503 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SPTR: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno- octulosonatecytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.864 |
ADR20737.1 | lpxK | Ftrac_0735 | Ftrac_3580 | KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR000644: IPR001347: IPR004800; KEGG: tcx:Tcr_0503 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SPTR: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.860 |
ADR20738.1 | ADR20737.1 | Ftrac_0736 | Ftrac_0735 | 2-dehydro-3-deoxyphosphooctonate aldolase; COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; InterPro IPR006218: IPR006269; KEGG: pru:PRU_0445 3-deoxy-8-phosphooctulonate synthase; PFAM: DAHP synthetase I/KDSA; SPTR: Putative uncharacterized protein; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase. | KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR000644: IPR001347: IPR004800; KEGG: tcx:Tcr_0503 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SPTR: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.996 |
ADR20738.1 | ADR21114.1 | Ftrac_0736 | Ftrac_1119 | 2-dehydro-3-deoxyphosphooctonate aldolase; COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; InterPro IPR006218: IPR006269; KEGG: pru:PRU_0445 3-deoxy-8-phosphooctulonate synthase; PFAM: DAHP synthetase I/KDSA; SPTR: Putative uncharacterized protein; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR005834: IPR010023: IPR006549; KEGG: mac:MA3766 acylneuraminate cytidylyltransferase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Phosphatase kdsC; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; HAD-superfamily hydrolase, subfamily IIIA. | 0.996 |
ADR20738.1 | ADR23114.1 | Ftrac_0736 | Ftrac_3139 | 2-dehydro-3-deoxyphosphooctonate aldolase; COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; InterPro IPR006218: IPR006269; KEGG: pru:PRU_0445 3-deoxy-8-phosphooctulonate synthase; PFAM: DAHP synthetase I/KDSA; SPTR: Putative uncharacterized protein; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase. | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.809 |
ADR20738.1 | ADR23444.1 | Ftrac_0736 | Ftrac_3472 | 2-dehydro-3-deoxyphosphooctonate aldolase; COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; InterPro IPR006218: IPR006269; KEGG: pru:PRU_0445 3-deoxy-8-phosphooctulonate synthase; PFAM: DAHP synthetase I/KDSA; SPTR: Putative uncharacterized protein; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.805 |
ADR20738.1 | ADR23502.1 | Ftrac_0736 | Ftrac_3532 | 2-dehydro-3-deoxyphosphooctonate aldolase; COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; InterPro IPR006218: IPR006269; KEGG: pru:PRU_0445 3-deoxy-8-phosphooctulonate synthase; PFAM: DAHP synthetase I/KDSA; SPTR: Putative uncharacterized protein; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.760 |
ADR20738.1 | kdsB | Ftrac_0736 | Ftrac_3214 | 2-dehydro-3-deoxyphosphooctonate aldolase; COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; InterPro IPR006218: IPR006269; KEGG: pru:PRU_0445 3-deoxy-8-phosphooctulonate synthase; PFAM: DAHP synthetase I/KDSA; SPTR: Putative uncharacterized protein; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase. | 3-deoxy-D-manno- octulosonatecytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.836 |
ADR20738.1 | lpxK | Ftrac_0736 | Ftrac_3580 | 2-dehydro-3-deoxyphosphooctonate aldolase; COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; InterPro IPR006218: IPR006269; KEGG: pru:PRU_0445 3-deoxy-8-phosphooctulonate synthase; PFAM: DAHP synthetase I/KDSA; SPTR: Putative uncharacterized protein; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.827 |
ADR21114.1 | ADR20737.1 | Ftrac_1119 | Ftrac_0735 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR005834: IPR010023: IPR006549; KEGG: mac:MA3766 acylneuraminate cytidylyltransferase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Phosphatase kdsC; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; HAD-superfamily hydrolase, subfamily IIIA. | KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR000644: IPR001347: IPR004800; KEGG: tcx:Tcr_0503 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SPTR: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.944 |
ADR21114.1 | ADR20738.1 | Ftrac_1119 | Ftrac_0736 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR005834: IPR010023: IPR006549; KEGG: mac:MA3766 acylneuraminate cytidylyltransferase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Phosphatase kdsC; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; HAD-superfamily hydrolase, subfamily IIIA. | 2-dehydro-3-deoxyphosphooctonate aldolase; COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; InterPro IPR006218: IPR006269; KEGG: pru:PRU_0445 3-deoxy-8-phosphooctulonate synthase; PFAM: DAHP synthetase I/KDSA; SPTR: Putative uncharacterized protein; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase. | 0.996 |
ADR21114.1 | ADR23114.1 | Ftrac_1119 | Ftrac_3139 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR005834: IPR010023: IPR006549; KEGG: mac:MA3766 acylneuraminate cytidylyltransferase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Phosphatase kdsC; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; HAD-superfamily hydrolase, subfamily IIIA. | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.586 |
ADR21114.1 | ADR23444.1 | Ftrac_1119 | Ftrac_3472 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR005834: IPR010023: IPR006549; KEGG: mac:MA3766 acylneuraminate cytidylyltransferase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Phosphatase kdsC; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; HAD-superfamily hydrolase, subfamily IIIA. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.552 |
ADR21114.1 | ADR23502.1 | Ftrac_1119 | Ftrac_3532 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR005834: IPR010023: IPR006549; KEGG: mac:MA3766 acylneuraminate cytidylyltransferase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Phosphatase kdsC; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; HAD-superfamily hydrolase, subfamily IIIA. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.470 |