STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR23426.1Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. (628 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.926
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.758
ADR23079.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001440: IPR003661: IPR003594: IPR004358: IPR 019734: IPR005467: IPR013026; KEGG: rbi:RB2501_13794 putative two component system histidine kinase/response regulator fusion protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Tetratricopeptide TPR_1 repeat-containing protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Tetratricopeptide repeat; SPTR: Sensor histidine kinase/response regulator; PFAM: Histidine kinase-, DNA gyrase B [...]
  
 0.705
ADR22763.1
Heat shock protein DnaJ domain protein; COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623: IPR013026: IPR003095; KEGG: chu:CHU_1443 DnaJ class chaperone; heat shock protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: DNAJ class chaperone; heat shock protein; PFAM: DnaJ domain.
  
 0.698
ADR20684.1
KEGG: chu:CHU_0324 DnaJ-like chaperone; heat shock protein; SPTR: Putative uncharacterized protein.
  
 0.686
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 0.686
ADR22244.1
Heat shock protein DnaJ domain protein; COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623: IPR003095; KEGG: drm:Dred_2495 chaperone protein DnaJ; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: Chaperone protein dnaJ; PFAM: DnaJ domain.
  
 0.686
ADR23246.1
InterPro IPR001623; KEGG: gfo:GFO_1973 DnaJ-like protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: DnaJ-like protein; PFAM: DnaJ domain.
  
 0.686
ADR23420.1
Heat shock protein DnaJ domain protein; COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623: IPR003095; KEGG: ddi:DDB_G0288639 DNAJ heat shock N-terminal domain-containing protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: DnaJ homolog subfamily C member 7 homolog; PFAM: DnaJ domain.
  
 0.686
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.673
Your Current Organism:
Marivirga tractuosa
NCBI taxonomy Id: 643867
Other names: Flexibacter tractuosus DSM 4126, Flexibacter tractuosus IFO 15989, M. tractuosa DSM 4126, Marivirga tractuosa DSM 4126, Marivirga tractuosa IFO 15989, Marivirga tractuosa str. DSM 4126, Marivirga tractuosa strain DSM 4126
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.