STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR23725.1COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: gfo:GFO_3443 Cys/Met metabolism pyridoxal-phosphate-dependent enzyme; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Cys/Met metabolism PLP-dependent enzyme superfamily protein; PFAM: Cys/Met metabolism PLP-dependent enzyme. (385 aa)    
Predicted Functional Partners:
ADR20805.1
Cystathionine beta-synthase; COGs: COG0031 Cysteine synthase; InterPro IPR001216: IPR000644: IPR001926; KEGG: sli:Slin_5829 cystathionine beta-synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; CBS domain containing protein; SMART: CBS domain containing protein; SPTR: Cysteine synthase; PFAM: CBS domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: cystathionine beta-synthase.
 0.991
ADR23595.1
COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterProIPR011822: IPR003726: IPR000489: IPR004223: IPR 006158: IPR003759; KEGG: gfo:GFO_0333 5-methyltetrahydrofolate--homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; Vitamin B12 dependent methionine synthase activation region; SPTR: 5-methyltetrahydrofolate:homocysteine methyltransferase-cobalamin binding domain; TIGRFAM: methionine synthase; PFAM: Pterin binding enzyme; Vi [...]
  
 
 0.968
ADR21138.1
COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR000277: IPR006235; KEGG: chu:CHU_0274 O-acetylhomoserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase.
 
 
0.930
ADR22839.1
COGs: COG0527 Aspartokinase; InterProIPR001048: IPR002912: IPR005106: IPR001342: IPR 001341: IPR011147: IPR018042: IPR019811; KEGG: cpi:Cpin_5429 aspartate kinase; PFAM: homoserine dehydrogenase; aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; TIGRFAM: aspartate kinase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, mo [...]
 
 
 0.924
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
 
 0.918
ADR20111.1
Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: rmr:Rmar_1177 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Cys/Met metabolism PLP-dependent enzyme; PFAM: Cys/Met metabolism PLP-dependent enzyme.
  
  
 
0.914
ADR21753.1
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176: IPR004839: IPR004838; KEGG: rbi:RB2501_02675 putative aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Putative aspartate aminotransferase; PFAM: Aminotransferase class I and II.
  
 
 0.914
ADR20941.1
COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005786: IPR001544; KEGG: sli:Slin_1098 branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: Branched-chain-amino-acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II.
   
 0.913
ADR21027.1
Aminotransferase class IV; COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR018300: IPR001544; KEGG: sli:Slin_1202 aminotransferase class IV; PFAM: aminotransferase class IV; SPTR: Aminotransferase class IV; PFAM: Aminotransferase class IV.
   
 0.913
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
   
 0.913
Your Current Organism:
Marivirga tractuosa
NCBI taxonomy Id: 643867
Other names: Flexibacter tractuosus DSM 4126, Flexibacter tractuosus IFO 15989, M. tractuosa DSM 4126, Marivirga tractuosa DSM 4126, Marivirga tractuosa IFO 15989, Marivirga tractuosa str. DSM 4126, Marivirga tractuosa strain DSM 4126
Server load: low (14%) [HD]