Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EEX08734.1alpha-methylacyl-CoA racemase; Identified by match to protein family HMM PF02515; Belongs to the CoA-transferase III family. (364 aa)    
Predicted Functional Partners:
EEX09063.1
NADP-dependent malic enzyme; Identified by match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949.
     
 0.598
EEX10113.1
NAD-dependent malic enzyme; Identified by match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949.
     
 0.598
EEX08066.1
methylmalonyl-CoA mutase; Identified by match to protein family HMM PF01642; match to protein family HMM PF02310; match to protein family HMM TIGR00640; match to protein family HMM TIGR00641.
    
 0.595
EEX08599.1
methylmalonyl-CoA mutase; Identified by match to protein family HMM PF01642; match to protein family HMM PF02310; match to protein family HMM TIGR00640; match to protein family HMM TIGR00641.
    
 0.595
EEX08425.1
Phosphate butyryltransferase; Identified by match to protein family HMM PF01515; match to protein family HMM PF01575.
  
 
 0.593
EEX09444.1
Hypothetical protein.
  
 
  0.584
sucD
succinyl-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
  0.563
EEX08241.1
Tungsten-containing formate dehydrogenase beta subunit; Identified by match to protein family HMM PF01257; match to protein family HMM PF01512.
     
  0.555
EEX08610.1
MaoC domain protein dehydratase.
  
 
  0.549
sucC
succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
  0.541
Your Current Organism:
Ruegeria lacuscaerulensis
NCBI taxonomy Id: 644107
Other names: R. lacuscaerulensis ITI-1157, Ruegeria lacuscaerulensis DSM 11314, Ruegeria lacuscaerulensis ITI-1157, Silicibacter lacuscaerulensis KCTC 2953
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