STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEX09723.1Methionine synthase, vitamin-B12 independent; Identified by match to protein family HMM PF01717. (374 aa)    
Predicted Functional Partners:
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 0.981
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
 0.978
EEX09722.1
Cupin 2 conserved barrel domain protein; Identified by match to protein family HMM PF07883.
 
  
  0.955
EEX09725.1
Conserved hypothetical protein.
 
     0.951
EEX10925.1
Methionine synthase I; Identified by match to protein family HMM PF02574.
  
 
 0.951
metF
5,10-methylenetetrahydrofolate reductase; Identified by match to protein family HMM PF02219; match to protein family HMM TIGR00676; Belongs to the methylenetetrahydrofolate reductase family.
  
 0.932
EEX11206.1
Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447.
   
 
 0.912
EEX10850.1
Methylenetetrahydrofolate reductase.
  
 0.910
EEX11140.1
O-acetylhomoserine (thiol)-lyase; Identified by match to protein family HMM PF01053; match to protein family HMM TIGR01326.
  
 
 0.909
EEX09724.1
Alpha/beta hydrolase; Identified by match to protein family HMM PF00561.
 
     0.905
Your Current Organism:
Ruegeria lacuscaerulensis
NCBI taxonomy Id: 644107
Other names: R. lacuscaerulensis ITI-1157, Ruegeria lacuscaerulensis DSM 11314, Ruegeria lacuscaerulensis ITI-1157, Silicibacter lacuscaerulensis KCTC 2953
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