STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C4QVM6_KOMPGKaryopherin/importin that interacts with the nuclear pore complex. (1117 aa)    
Predicted Functional Partners:
C4R3J1_KOMPG
THO complex subunit 4.
   
   0.957
C4R2V6_KOMPG
Ubl (Ubiquitin-like protein)-specific protease that cleaves Smt3p protein conjugates.
    
 
 0.935
C4R0Q2_KOMPG
GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
   
 
 0.916
C4R7C2_KOMPG
Karyopherin beta, forms a dimeric complex with Srp1p (Kap60p).
   
 
 0.832
C4R4T7_KOMPG
Essential component of the nuclear pore complex.
   
 
 0.826
C4R5P3_KOMPG
Essential component of the nuclear pore complex, which mediates nuclear import and export.
   
 
 0.826
C4QXD7_KOMPG
Protein phosphatase required for mitotic exit.
    
   0.818
C4R8J0_KOMPG
Nuclear pore complex subunit, part of a subcomplex also containing Nup53p, Nup170p, and Pse1p.
   
 
 0.818
C4R7B8_KOMPG
Uncharacterized protein.
   
 
 0.817
C4R2J6_KOMPG
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.778
Your Current Organism:
Komagataella phaffii
NCBI taxonomy Id: 644223
Other names: K. phaffii GS115, Komagataella phaffii GS115
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.