STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C4QVW3_KOMPGLipase_3 domain-containing protein. (529 aa)    
Predicted Functional Partners:
C4R069_KOMPG
TAG lipase / lysophosphatidylethanolamine acyltransferase.
    
 0.995
C4R8P1_KOMPG
Autophagy-related protein.
   
 
 0.983
C4QYQ0_KOMPG
Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy.
   
 
 0.982
C4R1B1_KOMPG
Protein serine/threonine kinase required for vesicle formation in autophagy.
   
 
 0.981
C4QY28_KOMPG
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
   
 
 0.980
C4R7Y7_KOMPG
Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.
   
 
 0.980
C4R4C0_KOMPG
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.
   
 
 0.979
C4QVF7_KOMPG
Peripheral membrane protein required for vesicle formation.
    
 
 0.978
C4R5A1_KOMPG
Autophagy-related protein 3.
   
 
 0.978
C4QZZ5_KOMPG
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II.
    
 
 0.973
Your Current Organism:
Komagataella phaffii
NCBI taxonomy Id: 644223
Other names: K. phaffii GS115, Komagataella phaffii GS115
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.