STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C4QYM3_KOMPGNucleolar protein, required for pre-25S rRNA processing. (445 aa)    
Predicted Functional Partners:
SPB1
AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
   
 
 0.952
C4R3Q1_KOMPG
Nucleolar protein, constituent of 66S pre-ribosomal particles.
   
 
 0.942
C4R3V5_KOMPG
Nucleolar protein.
   
 
 0.935
C4R667_KOMPG
Essential protein involved in the processing of pre-rRNA and the assembly of 60S ribosomal subunit.
   
 
 0.932
C4R3I8_KOMPG
Constituent of 66S pre-ribosomal particles, required for large (60S) ribosomal subunit biogenesis.
   
 
 0.928
C4R802_KOMPG
Uncharacterized protein.
   
 0.923
C4QZN4_KOMPG
Shuttling pre-60S factor.
   
 
 0.900
C4R5F2_KOMPG
Nucleolar DEAD-box protein required for ribosome assembly and function; Belongs to the DEAD box helicase family.
   
 0.898
ERB1
Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
   
  
 0.891
C4R1K0_KOMPG
Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis.
   
 
 0.880
Your Current Organism:
Komagataella phaffii
NCBI taxonomy Id: 644223
Other names: K. phaffii GS115, Komagataella phaffii GS115
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.