STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C4R0N6_KOMPGRNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (733 aa)    
Predicted Functional Partners:
C4R848_KOMPG
Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.
   
 0.995
C4R4Y0_KOMPG
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.990
C4R2R6_KOMPG
General transcription elongation factor TFIIS.
   
 0.977
C4R7H2_KOMPG
Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.
     
 0.974
C4R7L8_KOMPG
Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II.
   
 0.967
C4R7L2_KOMPG
RNA polymerase II third largest subunit B44, part of central core.
    
 0.957
C4R9A1_KOMPG
RNA polymerase II subunit.
    
 0.952
C4QZQ7_KOMPG
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.941
C4QYD9_KOMPG
Uncharacterized protein.
    
 0.922
C4R2U9_KOMPG
RNA polymerase II subunit B32.
    
 0.905
Your Current Organism:
Komagataella phaffii
NCBI taxonomy Id: 644223
Other names: K. phaffii GS115, Komagataella phaffii GS115
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